ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein tyrosine phosphatase, receptor type, B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127329 PTPRB 9606 - 12:70515866-70637440 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261266 PTPRB-007 70521403-70609844 protein_coding
  ENST00000334414 PTPRB-001 70515866-70637440 protein_coding
  ENST00000451516 PTPRB-201 70521317-70637421 protein_coding
  ENST00000538174 PTPRB-005 70584965-70637414 processed_transcript
  ENST00000538708 PTPRB-008 70521403-70609843 protein_coding
  ENST00000547715 PTPRB-010 70608729-70609788 protein_coding
  ENST00000548122 PTPRB-006 70559473-70637411 protein_coding
  ENST00000549400 PTPRB-011 70539414-70540059 retained_intron
  ENST00000550358 PTPRB-003 70521316-70637421 protein_coding
  ENST00000550857 PTPRB-009 70521403-70609843 protein_coding
  ENST00000551525 PTPRB-004 70558788-70637420 protein_coding
  ENST00000552253 PTPRB-002 70591734-70637440 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000261266ENST00000334414ENST00000451516ENST00000538708ENST00000550358ENST00000550857ENST00000551525ENST00000552253
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000261266 N/A 7.873±6.16 9.601±0.00 16.808±14.78
ENST00000334414 N/A 3.904±4.86 11.726±0.00 10.055±6.08
ENST00000451516 N/A 4.888±5.45 8.313±0.00 8.194±3.27
ENST00000538708 1.238±0.00 0.716±0.00 N/A N/A
ENST00000550358 N/A 3.529±2.51 6.842±0.00 7.690±3.50
ENST00000550857 1.670±0.00 N/A N/A 8.313±4.18
ENST00000551525 N/A N/A N/A 6.925±0.00
ENST00000552253 N/A N/A N/A 20.786±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002B8 CIL_0002B8_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005001 TAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0006470 TAS:IEA protein dephosphorylation
GO:0006796 TAS phosphate-containing compound metabolic process
GO:0016311 IDA:IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0043235 IDA receptor complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076624 ptprb protein_coding Danio_rerio
ENSMUSG00000020154 Ptprb protein_coding Mus_musculus

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