ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127955 GNAI1 9606 + 7:80133955-80219402 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000351004 GNAI1-001 80134788-80219402 protein_coding
  ENST00000418742 GNAI1-003 80135289-80203832 protein_coding
  ENST00000442586 GNAI1-004 80133955-80135228 protein_coding
  ENST00000447650 GNAI1-006 80187059-80189209 protein_coding
  ENST00000457358 GNAI1-002 80135755-80217861 protein_coding
  ENST00000490206 GNAI1-005 80134498-80189232 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000351004ENST00000418742ENST00000457358ENST00000490206
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000351004 1.708±0.00 2.002±1.17 4.626±0.00 2.776±2.20
ENST00000418742 N/A 2.951±0.02 N/A 1.809±0.53
ENST00000457358 N/A 2.889±1.44 8.526±0.00 2.655±1.33
ENST00000490206 N/A 4.187±1.77 N/A 5.874±3.47

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA:IBA GTPase activity
GO:0004871 IEA:IBA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 IEA:ISS GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005765 IDA lysosomal membrane
GO:0005813 IDA centrosome
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 IDA plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007049 IEA cell cycle
GO:0007165 IEA signal transduction
GO:0007186 IEA:ISS G-protein coupled receptor signaling pathway
GO:0007188 IEA:IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0019001 IEA guanyl nucleotide binding
GO:0030168 TAS platelet activation
GO:0030496 IDA midbody
GO:0031683 IEA:IBA G-protein beta/gamma-subunit complex binding
GO:0031821 IBA G-protein coupled serotonin receptor binding
GO:0043434 ISS response to peptide hormone
GO:0046872 IEA metal ion binding
GO:0051301 IMP cell division
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030644 gnai3 protein_coding Danio_rerio
ENSMUSG00000057614 Gnai1 protein_coding Mus_musculus

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