Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'cake_dev_eng'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = array(
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	(int) 1 => 'experiment',
	(int) 2 => 'expressed_transcripts',
	(int) 3 => 'genes',
	(int) 4 => 'go_annotations',
	(int) 5 => 'homologues',
	(int) 6 => 'repeats',
	(int) 7 => 'study',
	(int) 8 => 'synonyms',
	(int) 9 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_genes'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

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                ),
                E_USER_WARNING
            );
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		'collate' => 'latin1_swedish_ci',
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		'type' => 'string',
		'null' => true,
		'default' => null,
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		'collate' => 'latin1_swedish_ci',
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	'gene_description' => array(
		'type' => 'string',
		'null' => true,
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		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
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)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

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Gene Info
Description:	forkhead box P2
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000128573	FOXP2	9606	+	7:114086327-114693772	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000350908		FOXP2-001	114415055-114690100	protein_coding
	ENST00000360232		FOXP2-017	114426500-114654143	protein_coding
	ENST00000378237		FOXP2-010	114415319-114645830	protein_coding
	ENST00000390668		FOXP2-016	114426515-114654143	protein_coding
	ENST00000393489		FOXP2-020	114415323-114689957	protein_coding
	ENST00000393491		FOXP2-201	114414997-114693768	protein_coding
	ENST00000393494		FOXP2-014	114414274-114690163	protein_coding
	ENST00000393495		FOXP2-018	114415112-114642585	protein_coding
	ENST00000393498		FOXP2-005	114415058-114690145	protein_coding
	ENST00000403559		FOXP2-202	114414997-114693768	protein_coding
	ENST00000408937		FOXP2-004	114414997-114693772	protein_coding
	ENST00000412402		FOXP2-006	114086327-114690905	nonsense_mediated_decay
	ENST00000440349		FOXP2-002	114086439-114631584	nonsense_mediated_decay
	ENST00000441290		FOXP2-008	114086560-114669984	nonsense_mediated_decay
	ENST00000452963		FOXP2-015	114426502-114630005	protein_coding
	ENST00000459666		FOXP2-009	114415220-114628982	processed_transcript
	ENST00000462331		FOXP2-007	114414997-114499728	protein_coding
	ENST00000495516		FOXP2-011	114088166-114426510	processed_transcript

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID BECs HAoEC HUVEC ENST00000360232 N/A 0.083±0.00 0.217±0.19 ENST00000393489 N/A 0.005±0.00 0.076±0.01 ENST00000393491 0.095±0.00 0.028±0.02 0.043±0.03 ENST00000393494 N/A N/A 0.148±0.00 ENST00000393495 N/A N/A 0.046±0.00 ENST00000393498 N/A 0.027±0.01 0.056±0.03 ENST00000403559 N/A N/A 0.033±0.02 ENST00000408937 N/A N/A 0.023±0.01 ENST00000412402 N/A N/A 0.050±0.05 ENST00000440349 N/A 0.052±0.01 0.067±0.02 ENST00000441290 N/A 0.006±0.00 0.018±0.00 ENST00000452963 N/A 0.285±0.18 0.231±0.18 ENST00000459666 N/A 0.038±0.00 0.099±0.02 ENST00000462331 N/A 0.006±0.00 0.094±0.00

Conserved Regions
Region ID	Sub-Region	Region Type
CIL_00084L	CIL_00084L_0001	VISTA
CIL_00090T	CIL_00090T_0001	VISTA
CIL_000412	CIL_000412_0001	CGP
CIL_000411	CIL_000411_0001	CGP

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000122	IEA	negative regulation of transcription from RNA polymerase II promoter
GO:0000978	IEA	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078	IEA	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0002053	IEA	positive regulation of mesenchymal cell proliferation
GO:0003677	IDA	DNA binding
GO:0003700	IDA:IEA	sequence-specific DNA binding transcription factor activity
GO:0005515	IEA	protein binding
GO:0005634	IEA	nucleus
GO:0006351	IEA	transcription, DNA-templated
GO:0006355	IEA	regulation of transcription, DNA-templated
GO:0007519	IEA	skeletal muscle tissue development
GO:0009791	IEA	post-embryonic development
GO:0021549	IEA	cerebellum development
GO:0021757	IMP	caudate nucleus development
GO:0021758	IMP	putamen development
GO:0021987	IEP	cerebral cortex development
GO:0030324	IEA	lung development
GO:0040007	IEA	growth
GO:0042297	IEA	vocal learning
GO:0042803	IDA	protein homodimerization activity
GO:0043010	IEA	camera-type eye development
GO:0043565	IDA:IEA	sequence-specific DNA binding
GO:0045892	IDA	negative regulation of transcription, DNA-templated
GO:0046872	IEA	metal ion binding
GO:0046982	IEA	protein heterodimerization activity
GO:0048286	IEA	lung alveolus development
GO:0048745	IEA	smooth muscle tissue development
GO:0050679	IEA	positive regulation of epithelial cell proliferation
GO:0060013	IEA	righting reflex
GO:0060501	IEA	positive regulation of epithelial cell proliferation involved in lung morphogenesis

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000005453	foxp2		protein_coding	Danio_rerio
ENSMUSG00000029563	Foxp2		protein_coding	Mus_musculus

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

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                ),
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		'b7d572bb36c8f0f2ecfe36921c14fbf3' => '`Gene`.`chromosome`',
		'edf6b12f8a40424f91fa0a40f0eab275' => '`Gene`.`strand`',
		'71d92ec0ad29837870abd0de3ae8addc' => '`Gene`.`start`',
		'62e43d606bf4cdae2d6694c62e19e7fa' => '`Gene`.`end`',
		'7043386674301bd31c5e629dfdadabd4' => '`Gene`.`gene_name`',
		'f1454297621ddcf07c418e47f67d3857' => '`Gene`.`gene_source`',
		'27d53785bfcd771f1901030b4bb87d02' => '`Gene`.`gene_biotype`',
		'b93574bf8a03f2d6f6486e920115e0d1' => '`Gene`.`annotation_version`',
		'1c4a3f5d90070e8ea1c62ca077df603e' => '`Gene`.`gene_description`',
		'8ca7a0c53312b8ae3cfa40a9d814adac' => '`Gene`'
	),
	'fields' => array(
		'47cba37bb7792f95f7499f6996d48351' => array(
			(int) 0 => '`Gene`.`id`',
			(int) 1 => '`Gene`.`gene_version`',
			(int) 2 => '`Gene`.`tax_id`',
			(int) 3 => '`Gene`.`assembly`',
			(int) 4 => '`Gene`.`chromosome`',
			(int) 5 => '`Gene`.`strand`',
			(int) 6 => '`Gene`.`start`',
			(int) 7 => '`Gene`.`end`',
			(int) 8 => '`Gene`.`gene_name`',
			(int) 9 => '`Gene`.`gene_source`',
			(int) 10 => '`Gene`.`gene_biotype`',
			(int) 11 => '`Gene`.`annotation_version`',
			(int) 12 => '`Gene`.`gene_description`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??