ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phosphodiesterase 11A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128655 PDE11A 9606 - 2:177623252-178108339 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000286063 PDE11A-001 177623252-178072755 protein_coding
  ENST00000358450 PDE11A-002 177628069-178108339 protein_coding
  ENST00000389683 PDE11A-003 177629246-177888738 protein_coding
  ENST00000409504 PDE11A-004 177629047-177922795 protein_coding
  ENST00000427127 PDE11A-008 177898114-177922837 nonsense_mediated_decay
  ENST00000433879 PDE11A-006 177675455-177905174 protein_coding
  ENST00000436700 PDE11A-007 177628612-177675660 protein_coding
  ENST00000466790 PDE11A-009 177669531-177683470 processed_transcript
  ENST00000478646 PDE11A-011 177629175-177675552 retained_intron
  ENST00000488399 PDE11A-010 177629423-177676094 processed_transcript
  ENST00000492761 PDE11A-012 177797071-177888776 processed_transcript
  ENST00000497003 PDE11A-005 177686707-177927009 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000286063ENST00000358450ENST00000389683ENST00000409504ENST00000433879ENST00000436700ENST00000478646ENST00000488399ENST00000492761ENST00000497003
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000286063 0.014±0.00 0.046±0.03 N/A N/A 0.014±0.01
ENST00000358450 N/A 0.011±0.00 N/A N/A N/A
ENST00000389683 N/A N/A N/A N/A 0.024±0.02
ENST00000409504 N/A N/A N/A N/A 0.035±0.00
ENST00000433879 N/A 0.110±0.00 N/A N/A 0.034±0.02
ENST00000436700 N/A N/A N/A N/A 0.019±0.01
ENST00000478646 N/A 0.036±0.00 N/A N/A N/A
ENST00000488399 N/A N/A N/A N/A 0.084±0.00
ENST00000492761 N/A N/A N/A N/A 0.048±0.00
ENST00000497003 N/A 0.030±0.02 0.070±0.00 0.044±0.00 0.055±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000Z3 CIL_0000Z3_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004112 NAS cyclic-nucleotide phosphodiesterase activity
GO:0004114 TAS:IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004118 IDA cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0005575 ND cellular_component
GO:0005829 TAS cytosol
GO:0006198 IEA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0007596 TAS blood coagulation
GO:0030552 IEA cAMP binding
GO:0030553 IDA cGMP binding
GO:0043204 IEA perikaryon
GO:0046069 IEA cGMP catabolic process
GO:0046872 IEA metal ion binding
GO:0047555 IEA 3',5'-cyclic-GMP phosphodiesterase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063732 pde11a protein_coding Danio_rerio
ENSMUSG00000075270 Pde11a protein_coding Mus_musculus

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