ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin specific peptidase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129204 USP6 9606 + 17:5116438-5175034 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000250066 USP6-001 5128392-5175034 protein_coding
  ENST00000357482 USP6-004 5128815-5135003 retained_intron
  ENST00000572429 USP6-006 5128766-5133550 processed_transcript
  ENST00000572949 USP6-005 5128392-5175032 nonsense_mediated_decay
  ENST00000574788 USP6-002 5116438-5174991 protein_coding
  ENST00000575709 USP6-003 5128392-5175032 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000250066ENST00000572949ENST00000574788ENST00000575709
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000250066 N/A N/A N/A N/A 0.072±0.05
ENST00000572949 N/A 0.129±0.06 0.440±0.00 0.210±0.00 0.191±0.12
ENST00000574788 N/A 0.052±0.03 0.315±0.00 0.133±0.00 0.048±0.03
ENST00000575709 0.111±0.00 0.106±0.03 0.296±0.00 N/A 0.049±0.04

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 TAS nucleic acid binding
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005097 IEA Rab GTPase activator activity
GO:0005515 IPI protein binding
GO:0005516 IPI calmodulin binding
GO:0005737 IDA cytoplasm
GO:0005764 TAS lysosome
GO:0005886 IDA plasma membrane
GO:0006464 NAS cellular protein modification process
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0016579 IDA protein deubiquitination
GO:0032313 IEA regulation of Rab GTPase activity
GO:0032851 IEA positive regulation of Rab GTPase activity
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0055037 IDA recycling endosome
GO:0060627 IDA regulation of vesicle-mediated transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061895 usp32 protein_coding Danio_rerio
ENSMUSG00000000804 Usp32 protein_coding Mus_musculus

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