ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: transient receptor potential cation channel, subfamily M, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130529 TRPM4 9606 + 19:49157741-49211836 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252826 TRPM4-001 49157741-49211836 protein_coding
  ENST00000427978 TRPM4-006 49157815-49211680 protein_coding
  ENST00000594568 TRPM4-010 49167644-49168337 retained_intron
  ENST00000595071 TRPM4-008 49182526-49211836 retained_intron
  ENST00000595519 TRPM4-003 49157792-49211836 nonsense_mediated_decay
  ENST00000595882 TRPM4-012 49188868-49196716 retained_intron
  ENST00000596338 TRPM4-007 49157832-49211749 retained_intron
  ENST00000597316 TRPM4-013 49210734-49211834 protein_coding
  ENST00000598502 TRPM4-005 49157832-49211749 nonsense_mediated_decay
  ENST00000598691 TRPM4-009 49157741-49171373 protein_coding
  ENST00000598697 TRPM4-004 49157766-49211834 nonsense_mediated_decay
  ENST00000599459 TRPM4-014 49210601-49211400 retained_intron
  ENST00000599628 TRPM4-002 49157792-49159921 protein_coding
  ENST00000601347 TRPM4-011 49168627-49182755 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000252826ENST00000427978ENST00000595071ENST00000595519ENST00000596338ENST00000597316ENST00000598502ENST00000598697ENST00000599459ENST00000599628
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000252826 N/A 2.881±1.69 N/A 4.033±3.16
ENST00000427978 N/A 2.106±0.99 N/A 0.882±0.72
ENST00000595071 5.291±0.42 N/A 11.619±0.00 2.485±2.30
ENST00000595519 5.150±0.00 2.530±0.87 N/A 1.472±1.01
ENST00000596338 N/A N/A N/A 1.805±1.26
ENST00000597316 25.174±0.00 N/A N/A N/A
ENST00000598502 3.334±0.00 N/A 4.395±0.00 2.422±0.72
ENST00000598697 N/A 2.517±0.47 N/A 1.679±0.00
ENST00000599459 37.893±11.80 N/A N/A N/A
ENST00000599628 N/A N/A N/A 1.236±0.54

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003AT CIL_0003AT_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002407 ISS dendritic cell chemotaxis
GO:0002724 IDA regulation of T cell cytokine production
GO:0005216 IEA ion channel activity
GO:0005227 ISS calcium activated cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006811 IEA ion transport
GO:0006816 IEA calcium ion transport
GO:0008284 IDA positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016925 IDA protein sumoylation
GO:0034220 TAS ion transmembrane transport
GO:0042310 IEA vasoconstriction
GO:0042391 IEA regulation of membrane potential
GO:0055085 TAS:IEA transmembrane transport
GO:0061337 IEA cardiac conduction
GO:0070588 TAS calcium ion transmembrane transport
GO:0090263 IDA positive regulation of canonical Wnt signaling pathway
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059993 trpm4a protein_coding Danio_rerio
ENSDARG00000063347 TRPM4 (3 of 4) protein_coding Danio_rerio
ENSDARG00000063435 trpm4b.2 protein_coding Danio_rerio
ENSMUSG00000038260 Trpm4 protein_coding Mus_musculus

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