ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: p21 protein (Cdc42/Rac)-activated kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130669 PAK4 9606 + 19:39125770-39182816 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321944 PAK4-011 39125798-39179401 protein_coding
  ENST00000358301 PAK4-003 39125802-39179402 protein_coding
  ENST00000360442 PAK4-201 39168611-39179406 protein_coding
  ENST00000593480 PAK4-010 39125799-39173107 protein_coding
  ENST00000593690 PAK4-004 39125814-39179401 protein_coding
  ENST00000597715 PAK4-007 39174936-39178764 protein_coding
  ENST00000597766 PAK4-009 39125813-39152392 processed_transcript
  ENST00000599386 PAK4-015 39125834-39182816 protein_coding
  ENST00000599470 PAK4-001 39125782-39178817 protein_coding
  ENST00000599657 PAK4-006 39156702-39173651 protein_coding
  ENST00000600350 PAK4-008 39176489-39178610 retained_intron
  ENST00000602004 PAK4-005 39125770-39173803 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000321944ENST00000358301ENST00000597715ENST00000599386ENST00000599470
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000321944 10.442±0.61 9.211±3.82 8.042±0.00 3.514±0.00 7.748±6.96
ENST00000358301 10.815±1.71 6.807±3.09 3.282±0.00 9.748±0.00 10.967±10.36
ENST00000597715 18.685±0.00 N/A N/A N/A N/A
ENST00000599386 N/A N/A N/A N/A 0.403±0.14
ENST00000599470 N/A 4.054±1.50 N/A N/A 0.647±0.41

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005794 TAS Golgi apparatus
GO:0005925 IDA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0006928 TAS cellular component movement
GO:0007010 TAS cytoskeleton organization
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0008283 TAS cell proliferation
GO:0016049 TAS cell growth
GO:0016477 TAS cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018110 pak4 protein_coding Danio_rerio

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