ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Cdc42 guanine nucleotide exchange factor (GEF) 9
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131089 ARHGEF9 9606 - X:63634967-63809274 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253401 ARHGEF9-001 63634967-63755113 protein_coding
  ENST00000374870 ARHGEF9-013 63634971-63755089 protein_coding
  ENST00000374872 ARHGEF9-004 63637982-63755127 protein_coding
  ENST00000374878 ARHGEF9-002 63634967-63785546 protein_coding
  ENST00000437457 ARHGEF9-008 63636331-63785524 protein_coding
  ENST00000466925 ARHGEF9-006 63637982-63674138 protein_coding
  ENST00000495564 ARHGEF9-003 63637746-63755143 nonsense_mediated_decay
  ENST00000498761 ARHGEF9-005 63637982-63644266 retained_intron
  ENST00000623417 ARHGEF9-019 63678496-63809274 protein_coding
  ENST00000623517 ARHGEF9-007 63637690-63785558 protein_coding
  ENST00000623566 ARHGEF9-016 63697221-63755335 protein_coding
  ENST00000623951 ARHGEF9-015 63754284-63755070 processed_transcript
  ENST00000624210 ARHGEF9-014 63637840-63755078 protein_coding
  ENST00000624355 ARHGEF9-009 63697276-63785215 protein_coding
  ENST00000624387 ARHGEF9-018 63706263-63724975 processed_transcript
  ENST00000624538 ARHGEF9-017 63724532-63755032 protein_coding
  ENST00000624783 ARHGEF9-020 63637982-63657990 processed_transcript
  ENST00000624843 ARHGEF9-010 63637985-63755063 protein_coding
  ENST00000625116 ARHGEF9-011 63678504-63785215 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000253401ENST00000374870ENST00000374872ENST00000374878ENST00000466925ENST00000495564ENST00000623951ENST00000624210ENST00000624538ENST00000624783ENST00000624843
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000253401 0.122±0.00 0.513±0.15 N/A N/A 0.596±0.35
ENST00000374870 0.436±0.03 N/A N/A N/A 0.272±0.11
ENST00000374872 N/A 0.558±0.00 N/A N/A 0.962±0.02
ENST00000374878 N/A N/A 1.266±0.00 N/A N/A
ENST00000466925 2.028±0.00 N/A N/A N/A N/A
ENST00000495564 N/A N/A N/A N/A 0.158±0.00
ENST00000623951 N/A N/A N/A N/A 1.398±0.46
ENST00000624210 0.434±0.00 1.235±0.38 N/A 0.685±0.00 1.239±0.78
ENST00000624538 N/A N/A N/A N/A 0.556±0.00
ENST00000624783 6.951±2.35 N/A 7.806±0.00 N/A N/A
ENST00000624843 N/A 1.052±0.19 N/A N/A 0.559±0.29

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002RM CIL_0002RM_0001 CGP
CIL_0003JJ CIL_0003JJ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005829 TAS cytosol
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007268 TAS synaptic transmission
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0034220 TAS ion transmembrane transport
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0055085 TAS transmembrane transport
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061746 arhgef9a protein_coding Danio_rerio
ENSDARG00000078624 arhgef9b protein_coding Danio_rerio
ENSMUSG00000025656 Arhgef9 protein_coding Mus_musculus

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