ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 6 (neurotransmitter transporter), member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131389 SLC6A6 9606 + 3:14402576-14489349 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000452151 SLC6A6-011 14472242-14484903 protein_coding
  ENST00000452775 SLC6A6-009 14432670-14445816 protein_coding
  ENST00000610642 SLC6A6-002 14402576-14478901 nonsense_mediated_decay
  ENST00000613060 SLC6A6-001 14402576-14489349 protein_coding
  ENST00000613930 SLC6A6-003 14402621-14444342 retained_intron
  ENST00000615188 SLC6A6-007 14402648-14458026 processed_transcript
  ENST00000618278 SLC6A6-006 14402576-14489349 nonsense_mediated_decay
  ENST00000621751 SLC6A6-004 14402620-14448188 protein_coding
  ENST00000622176 SLC6A6-005 14402625-14458061 nonsense_mediated_decay
  ENST00000622186 SLC6A6-201 14402576-14489347 protein_coding
  ENST00000622810 SLC6A6-008 14402576-14411323 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000610642ENST00000613060ENST00000618278ENST00000622186
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000610642 N/A N/A N/A 3.915±2.52
ENST00000613060 0.382±0.00 0.928±0.00 N/A 1.839±0.00
ENST00000618278 N/A 1.931±0.59 N/A N/A
ENST00000622186 0.862±0.48 4.773±1.81 12.828±0.00 6.676±2.92

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007GZ CIL_0007GZ_0001 CGP
CIL_000514 CIL_000514_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005368 IEA taurine transmembrane transporter activity
GO:0005369 IEA taurine:sodium symporter activity
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006520 TAS cellular amino acid metabolic process
GO:0006810 TAS transport
GO:0006811 TAS ion transport
GO:0006836 IEA neurotransmitter transport
GO:0006865 TAS amino acid transport
GO:0015734 IEA taurine transport
GO:0016021 IEA integral component of membrane
GO:0030977 IEA taurine binding
GO:0055085 IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012534 slc6a6a protein_coding Danio_rerio
ENSMUSG00000030096 Slc6a6 protein_coding Mus_musculus

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