ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin-conjugating enzyme E2D 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131508 UBE2D2 9606 + 5:139526431-139628433 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253815 UBE2D2-201 139599562-139626801 protein_coding
  ENST00000398733 UBE2D2-001 139561166-139628433 protein_coding
  ENST00000398734 UBE2D2-004 139561726-139627686 nonsense_mediated_decay
  ENST00000505007 UBE2D2-003 139561167-139623444 protein_coding
  ENST00000505548 UBE2D2-002 139562029-139627115 protein_coding
  ENST00000510470 UBE2D2-007 139561724-139614685 retained_intron
  ENST00000511691 UBE2D2-008 139600404-139623662 retained_intron
  ENST00000511725 UBE2D2-006 139526431-139626855 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000253815ENST00000398733ENST00000398734ENST00000505007ENST00000505548ENST00000510470
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000253815 74.737±8.83 66.478±12.86 48.449±0.00 68.726±0.00 56.677±21.48
ENST00000398733 14.790±2.93 14.479±7.13 9.477±0.00 22.006±0.00 15.738±9.15
ENST00000398734 19.045±0.00 23.429±7.50 N/A 31.530±0.00 19.134±6.81
ENST00000505007 N/A N/A N/A N/A 9.110±5.32
ENST00000505548 N/A N/A N/A N/A 1.965±0.44
ENST00000510470 N/A N/A N/A N/A 38.909±10.44

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000548 CIL_000548_0001 CGP
CIL_000549 CIL_000549_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000209 IDA protein polyubiquitination
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006464 TAS cellular protein modification process
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0008152 IEA metabolic process
GO:0016567 IDA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0043234 IDA protein complex
GO:0045087 TAS innate immune response
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 IDA extracellular vesicular exosome
GO:0070936 IDA protein K48-linked ubiquitination
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000063447 Ube2d2b protein_coding Mus_musculus
ENSMUSG00000091896 Ube2d2a protein_coding Mus_musculus

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