ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: lysine (K)-specific demethylase 6B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132510 KDM6B 9606 + 17:7839904-7854796 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254846 KDM6B-001 7839904-7854796 protein_coding
  ENST00000448097 KDM6B-002 7839962-7853680 protein_coding
  ENST00000570632 KDM6B-003 7844915-7847571 protein_coding
  ENST00000571047 KDM6B-004 7839904-7845347 processed_transcript
  ENST00000572030 KDM6B-006 7839991-7840681 processed_transcript
  ENST00000575521 KDM6B-005 7844207-7844972 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000254846ENST00000448097ENST00000570632
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000254846 0.430±0.16 0.606±0.25 5.790±0.00 N/A 2.208±1.79
ENST00000448097 N/A 0.909±0.57 N/A N/A 1.234±1.05
ENST00000570632 N/A 0.421±0.00 N/A 1.356±0.00 0.131±0.08

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00037F CIL_00037F_0002 CGP
CIL_000322 CIL_000322_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0006954 IEA inflammatory response
GO:0008013 IEA beta-catenin binding
GO:0016577 IEA histone demethylation
GO:0043565 IEA sequence-specific DNA binding
GO:0045446 ISS endothelial cell differentiation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048333 ISS mesodermal cell differentiation
GO:0051213 IEA dioxygenase activity
GO:0055007 ISS cardiac muscle cell differentiation
GO:0055114 IEA oxidation-reduction process
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071557 IEA histone H3-K27 demethylation
GO:0071558 EXP histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088087 KDM6B protein_coding Danio_rerio
ENSMUSG00000018476 Kdm6b protein_coding Mus_musculus

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