| Transcript ID | BECs | HAoEC | HHSEC | HMVEC-D | HUVEC |
|---|---|---|---|---|---|
| ENST00000254846 | 0.430±0.16 | 0.606±0.25 | 5.790±0.00 | N/A | 2.208±1.79 |
| ENST00000448097 | N/A | 0.909±0.57 | N/A | N/A | 1.234±1.05 |
| ENST00000570632 | N/A | 0.421±0.00 | N/A | 1.356±0.00 | 0.131±0.08 |
Gene Info | |||||
|---|---|---|---|---|---|
| Description: | lysine (K)-specific demethylase 6B | ||||
| Gene Accession | Gene Name | Tax ID | Strand | Position | Gene Biotype |
|
ENSG00000132510 |
KDM6B | 9606 | + |
17:7839904-7854796 |
protein_coding |
| Transcript Accession | Transcript Name | Position | Transcript Biotype | ||
| ENST00000254846 |
KDM6B-001 | 7839904-7854796 | protein_coding | ||
| ENST00000448097 |
KDM6B-002 | 7839962-7853680 | protein_coding | ||
| ENST00000570632 |
KDM6B-003 | 7844915-7847571 | protein_coding | ||
| ENST00000571047 |
KDM6B-004 | 7839904-7845347 | processed_transcript | ||
| ENST00000572030 |
KDM6B-006 | 7839991-7840681 | processed_transcript | ||
| ENST00000575521 |
KDM6B-005 | 7844207-7844972 | processed_transcript | ||
Expression Patterns
|
Conserved Regions | ||
|---|---|---|
| Region ID | Sub-Region | Region Type |
| CIL_00037F | CIL_00037F_0002 | CGP |
| CIL_000322 | CIL_000322_0002 | CGP |
Gene Ontology |
||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0005515 | IPI | protein binding |
| GO:0005634 | ISS | nucleus |
| GO:0005654 | TAS | nucleoplasm |
| GO:0006954 | IEA | inflammatory response |
| GO:0008013 | IEA | beta-catenin binding |
| GO:0016577 | IEA | histone demethylation |
| GO:0043565 | IEA | sequence-specific DNA binding |
| GO:0045446 | ISS | endothelial cell differentiation |
| GO:0045944 | ISS | positive regulation of transcription from RNA polymerase II promoter |
| GO:0046872 | IEA | metal ion binding |
| GO:0048333 | ISS | mesodermal cell differentiation |
| GO:0051213 | IEA | dioxygenase activity |
| GO:0055007 | ISS | cardiac muscle cell differentiation |
| GO:0055114 | IEA | oxidation-reduction process |
| GO:0070301 | IEA | cellular response to hydrogen peroxide |
| GO:0071557 | IEA | histone H3-K27 demethylation |
| GO:0071558 | EXP | histone demethylase activity (H3-K27 specific) |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Description | Biotype | Species | |
|
ENSDARG00000088087
|
KDM6B | protein_coding | Danio_rerio | ||
|
ENSMUSG00000018476
|
Kdm6b | protein_coding | Mus_musculus | ||