ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132570 PCBD2 9606 + 5:134904906-135007959 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254908 PCBD2-001 134904906-134961277 protein_coding
  ENST00000504352 PCBD2-005 134905173-135007959 nonsense_mediated_decay
  ENST00000510013 PCBD2-004 134908830-134959095 processed_transcript
  ENST00000512783 PCBD2-002 134905120-134969660 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000254908ENST00000504352ENST00000510013ENST00000512783
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000254908 2.388±1.04 1.802±0.90 1.203±0.00 2.608±0.00 3.296±1.72
ENST00000504352 1.768±0.00 N/A N/A N/A N/A
ENST00000510013 N/A 4.421±0.01 N/A N/A N/A
ENST00000512783 0.154±0.00 0.296±0.15 0.311±0.00 0.330±0.00 0.468±0.18

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007JT CIL_0007JT_0002 UCNEbase
CIL_0009AP CIL_0009AP_0001 VISTA
CIL_0005XS CIL_0005XS_0001 CGP
CIL_0005XV CIL_0005XV_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004505 IEA phenylalanine 4-monooxygenase activity
GO:0005515 IPI protein binding
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0006729 IEA tetrahydrobiopterin biosynthetic process
GO:0008124 IEA 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0051289 IEA protein homotetramerization
GO:0051291 IEA protein heterooligomerization
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021496 Pcbd2 protein_coding Mus_musculus

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