ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: leucyl-tRNA synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133706 LARS 9606 - 5:146113038-146182660 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274562 LARS-201 146113896-146182524 protein_coding
  ENST00000394434 LARS-001 146113038-146182660 protein_coding
  ENST00000503654 LARS-011 146168229-146182520 processed_transcript
  ENST00000504323 LARS-005 146142959-146144731 retained_intron
  ENST00000504611 LARS-014 146129083-146130557 retained_intron
  ENST00000505223 LARS-012 146164398-146182650 processed_transcript
  ENST00000506231 LARS-003 146113911-146132626 retained_intron
  ENST00000506436 LARS-010 146172691-146182475 retained_intron
  ENST00000507095 LARS-006 146143487-146151907 processed_transcript
  ENST00000508667 LARS-004 146143244-146151948 retained_intron
  ENST00000508709 LARS-015 146123979-146130216 retained_intron
  ENST00000510191 LARS-002 146113911-146182623 protein_coding
  ENST00000511505 LARS-013 146157397-146182649 processed_transcript
  ENST00000512412 LARS-008 146133057-146143538 processed_transcript
  ENST00000514104 LARS-007 146142782-146144333 retained_intron
  ENST00000618084 LARS-202 146164315-146182625 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000274562ENST00000394434ENST00000505223ENST00000510191
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000274562 14.104±0.00 9.597±2.38 7.541±0.00 N/A 6.887±2.65
ENST00000394434 N/A 6.793±2.40 N/A 11.271±0.00 6.076±2.78
ENST00000505223 N/A N/A N/A N/A 51.958±6.57
ENST00000510191 N/A 15.055±3.86 N/A 24.139±0.00 14.435±5.53

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001GF CIL_0001GF_0002 CGP
CIL_0001J0 CIL_0001J0_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0002161 IEA aminoacyl-tRNA editing activity
GO:0004812 IEA aminoacyl-tRNA ligase activity
GO:0004823 IEA:TAS leucine-tRNA ligase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006418 IEA tRNA aminoacylation for protein translation
GO:0006429 IEA leucyl-tRNA aminoacylation
GO:0006450 IEA regulation of translational fidelity
GO:0010467 TAS gene expression

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019280 larsb protein_coding Danio_rerio
ENSDARG00000089031 larsa protein_coding Danio_rerio
ENSDARG00000090988 larsa protein_coding Danio_rerio
ENSMUSG00000024493 Lars protein_coding Mus_musculus

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