ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134248 LAMTOR5 9606 - 1:110401249-110407942 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256644 LAMTOR5-001 110401253-110407942 protein_coding
  ENST00000464240 LAMTOR5-002 110401249-110407694 retained_intron
  ENST00000474861 LAMTOR5-003 110401249-110407671 protein_coding
  ENST00000483260 LAMTOR5-004 110401249-110407668 protein_coding
  ENST00000531779 LAMTOR5-006 110403609-110407664 retained_intron
  ENST00000602318 LAMTOR5-007 110401253-110407708 protein_coding
  ENST00000602858 LAMTOR5-008 110401257-110406425 protein_coding
  ENST00000614544 LAMTOR5-201 110401257-110407924 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000464240ENST00000474861ENST00000602318ENST00000602858ENST00000614544
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000464240 N/A N/A N/A N/A 2.587±1.90
ENST00000474861 N/A N/A N/A N/A 4.035±0.45
ENST00000602318 142.013±14.80 149.532±39.01 40.283±0.00 115.382±0.00 164.743±93.27
ENST00000602858 78.472±17.92 N/A 92.967±0.00 N/A N/A
ENST00000614544 N/A N/A N/A N/A 0.375±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005764 IDA lysosome
GO:0005829 IDA cytosol
GO:0008361 IMP regulation of cell size
GO:0009615 TAS response to virus
GO:0019079 IEA viral genome replication
GO:0032008 IMP positive regulation of TOR signaling
GO:0032947 IDA protein complex scaffold
GO:0043066 IEA:IDA negative regulation of apoptotic process
GO:0043154 IEA:IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547 IDA positive regulation of GTPase activity
GO:0061462 IMP protein localization to lysosome
GO:0071230 IMP cellular response to amino acid stimulus
GO:0071986 IDA Ragulator complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090194 lamtor5 protein_coding Danio_rerio
ENSMUSG00000087260 Lamtor5 protein_coding Mus_musculus

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