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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: lactate dehydrogenase A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134333 LDHA 9606 + 11:18394388-18408425 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227157 LDHA-003 18394586-18408218 protein_coding
  ENST00000375710 LDHA-023 18399726-18407584 retained_intron
  ENST00000379412 LDHA-005 18396278-18407847 protein_coding
  ENST00000396222 LDHA-002 18394562-18408218 protein_coding
  ENST00000422447 LDHA-001 18394388-18408425 protein_coding
  ENST00000430553 LDHA-010 18394562-18407667 protein_coding
  ENST00000460405 LDHA-008 18398866-18403784 retained_intron
  ENST00000469976 LDHA-006 18394561-18397398 retained_intron
  ENST00000478970 LDHA-009 18394612-18401025 protein_coding
  ENST00000486690 LDHA-017 18396818-18405495 nonsense_mediated_decay
  ENST00000494573 LDHA-007 18394563-18400360 retained_intron
  ENST00000495052 LDHA-004 18394704-18400936 protein_coding
  ENST00000535451 LDHA-014 18394563-18399521 protein_coding
  ENST00000536528 LDHA-021 18394563-18403811 nonsense_mediated_decay
  ENST00000537296 LDHA-022 18398630-18405574 retained_intron
  ENST00000538451 LDHA-024 18402535-18407740 retained_intron
  ENST00000539814 LDHA-016 18394563-18400934 nonsense_mediated_decay
  ENST00000540430 LDHA-201 18396266-18408218 protein_coding
  ENST00000541097 LDHA-019 18394563-18407158 nonsense_mediated_decay
  ENST00000542179 LDHA-020 18396554-18407281 protein_coding
  ENST00000543445 LDHA-013 18394560-18402891 protein_coding
  ENST00000543695 LDHA-015 18394563-18403759 nonsense_mediated_decay
  ENST00000545215 LDHA-011 18394563-18407642 nonsense_mediated_decay
  ENST00000545467 LDHA-018 18394562-18400872 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000227157ENST00000379412ENST00000396222ENST00000422447ENST00000430553ENST00000538451ENST00000541097ENST00000543445ENST00000545215
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000227157 50.203±7.41 N/A 16.972±0.00 N/A N/A
ENST00000379412 N/A 74.720±32.42 N/A 53.771±0.00 22.339±11.46
ENST00000396222 96.711±1.32 111.589±31.30 25.501±0.00 53.918±0.00 60.437±34.07
ENST00000422447 N/A N/A N/A N/A 8.541±0.00
ENST00000430553 N/A 139.340±9.38 N/A N/A 48.475±25.32
ENST00000538451 144.439±67.99 N/A 27.509±0.00 N/A 65.035±0.00
ENST00000541097 N/A N/A N/A N/A 126.469±32.62
ENST00000543445 N/A N/A N/A N/A 10.317±3.41
ENST00000545215 N/A 118.215±30.99 N/A 132.650±0.00 92.447±44.21

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000445 CIL_000445_0001 CGP
CIL_000369 CIL_000369_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004459 NAS L-lactate dehydrogenase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005975 IEA carbohydrate metabolic process
GO:0006090 TAS pyruvate metabolic process
GO:0006096 NAS glycolytic process
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0021762 IEP substantia nigra development
GO:0031668 IEA cellular response to extracellular stimulus
GO:0035686 IEA sperm fibrous sheath
GO:0044237 TAS cellular metabolic process
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000063229 Ldha protein_coding Mus_musculus

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