ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SRY (sex determining region Y)-box 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134532 SOX5 9606 - 12:23529500-23951032 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367206 SOX5-006 23536530-23950920 nonsense_mediated_decay
  ENST00000381381 SOX5-201 23532298-23949703 protein_coding
  ENST00000396007 SOX5-001 23534034-23584612 protein_coding
  ENST00000441133 SOX5-004 23762475-23951020 protein_coding
  ENST00000451604 SOX5-002 23532352-23949703 protein_coding
  ENST00000535530 SOX5-014 23563316-23738506 processed_transcript
  ENST00000536629 SOX5-015 23575813-23738506 processed_transcript
  ENST00000536850 SOX5-011 23920038-23949592 processed_transcript
  ENST00000536911 SOX5-013 23603921-23734715 retained_intron
  ENST00000537393 SOX5-008 23533683-23949647 protein_coding
  ENST00000538083 SOX5-010 23845991-23944352 protein_coding
  ENST00000541536 SOX5-009 23533787-23896027 protein_coding
  ENST00000541847 SOX5-016 23740851-23950907 protein_coding
  ENST00000542241 SOX5-012 23575659-23632194 processed_transcript
  ENST00000545921 SOX5-007 23534048-23951032 protein_coding
  ENST00000546136 SOX5-003 23529500-23896026 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000367206ENST00000381381ENST00000396007ENST00000441133ENST00000451604ENST00000535530ENST00000536629ENST00000536911ENST00000537393ENST00000538083ENST00000541536ENST00000541847ENST00000542241ENST00000545921ENST00000546136
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000367206 N/A N/A N/A N/A 0.302±0.27
ENST00000381381 0.022±0.00 0.043±0.00 N/A 0.031±0.00 0.018±0.01
ENST00000396007 N/A 0.051±0.02 N/A N/A 0.064±0.05
ENST00000441133 N/A 0.144±0.02 N/A N/A 0.205±0.08
ENST00000451604 N/A N/A N/A N/A 0.019±0.00
ENST00000535530 N/A N/A N/A N/A 0.043±0.00
ENST00000536629 N/A N/A N/A N/A 0.671±0.62
ENST00000536911 N/A 0.064±0.02 N/A N/A 0.124±0.00
ENST00000537393 N/A N/A 0.018±0.00 N/A 0.067±0.02
ENST00000538083 N/A 0.073±0.04 N/A N/A 0.192±0.15
ENST00000541536 N/A 0.034±0.00 N/A N/A 0.109±0.07
ENST00000541847 N/A 0.127±0.01 N/A N/A 0.663±0.67
ENST00000542241 N/A 0.149±0.00 0.213±0.00 N/A 0.166±0.00
ENST00000545921 N/A N/A N/A N/A 0.066±0.04
ENST00000546136 N/A 0.013±0.01 0.017±0.00 N/A 0.040±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006Y0 CIL_0006Y0_0002 CGP
CIL_0007NR CIL_0007NR_0001 UCNEbase
CIL_0004XB CIL_0004XB_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001701 IEA in utero embryonic development
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0021953 IEA central nervous system neuron differentiation
GO:0032332 IDA positive regulation of chondrocyte differentiation
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044798 IEA nuclear transcription factor complex
GO:0045165 IEA cell fate commitment
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048709 IEA oligodendrocyte differentiation
GO:0051216 IEA cartilage development
GO:0060164 IEA regulation of timing of neuron differentiation
GO:0061036 IDA positive regulation of cartilage development
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:2000741 IDA positive regulation of mesenchymal stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011582 sox5 protein_coding Danio_rerio
ENSMUSG00000041540 Sox5 protein_coding Mus_musculus

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