ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: damage-specific DNA binding protein 2, 48kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134574 DDB2 9606 + 11:47214465-47239240 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256996 DDB2-001 47214942-47239240 protein_coding
  ENST00000378600 DDB2-006 47215137-47238849 protein_coding
  ENST00000378601 DDB2-002 47214992-47239189 nonsense_mediated_decay
  ENST00000378603 DDB2-007 47215137-47238849 protein_coding
  ENST00000610805 DDB2-014 47215088-47232959 nonsense_mediated_decay
  ENST00000612309 DDB2-003 47215095-47239217 retained_intron
  ENST00000614394 DDB2-010 47234581-47236087 retained_intron
  ENST00000614825 DDB2-012 47214570-47234653 protein_coding
  ENST00000614884 DDB2-016 47237806-47239217 retained_intron
  ENST00000615695 DDB2-015 47215058-47217411 retained_intron
  ENST00000616278 DDB2-004 47215137-47238849 nonsense_mediated_decay
  ENST00000617022 DDB2-005 47215112-47239216 retained_intron
  ENST00000617847 DDB2-008 47216913-47239191 nonsense_mediated_decay
  ENST00000620515 DDB2-009 47234627-47237900 processed_transcript
  ENST00000622090 DDB2-013 47215045-47232836 protein_coding
  ENST00000622878 DDB2-011 47214465-47216873 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000256996ENST00000378601ENST00000378603ENST00000612309ENST00000614394ENST00000614825ENST00000614884
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000256996 11.222±0.00 13.550±6.87 N/A 5.955±0.00 16.667±11.40
ENST00000378601 N/A 2.687±0.00 N/A 7.549±0.00 11.788±3.24
ENST00000378603 N/A N/A N/A 8.187±0.00 N/A
ENST00000612309 N/A 5.117±2.10 N/A N/A 6.631±6.63
ENST00000614394 N/A N/A 2.743±0.00 N/A 13.208±0.00
ENST00000614825 N/A 9.424±3.32 N/A 9.641±0.00 N/A
ENST00000614884 87.861±18.08 21.216±9.80 7.022±0.00 14.024±0.00 27.742±5.91

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0003677 TAS DNA binding
GO:0003684 IDA damaged DNA binding
GO:0003824 IEA catalytic activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0006281 TAS DNA repair
GO:0006289 TAS nucleotide-excision repair
GO:0006290 IEA pyrimidine dimer repair
GO:0009411 IDA response to UV
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0035518 IDA histone H2A monoubiquitination
GO:0043234 IDA protein complex
GO:0051865 IDA protein autoubiquitination
GO:0070914 IDA UV-damage excision repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041140 ddb2 protein_coding Danio_rerio
ENSMUSG00000002109 Ddb2 protein_coding Mus_musculus

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