ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: glycoprotein (transmembrane) nmb
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136235 GPNMB 9606 + 7:23235967-23275108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258733 GPNMB-001 23246563-23275108 protein_coding
  ENST00000381990 GPNMB-002 23246697-23275107 protein_coding
  ENST00000409458 GPNMB-007 23246709-23258048 protein_coding
  ENST00000459927 GPNMB-003 23246766-23253367 processed_transcript
  ENST00000463011 GPNMB-009 23273081-23274252 processed_transcript
  ENST00000465673 GPNMB-013 23235967-23260053 processed_transcript
  ENST00000468723 GPNMB-011 23273293-23274550 retained_intron
  ENST00000470994 GPNMB-012 23270043-23273925 processed_transcript
  ENST00000474157 GPNMB-004 23246774-23247367 processed_transcript
  ENST00000478451 GPNMB-010 23273269-23274729 processed_transcript
  ENST00000479625 GPNMB-008 23266140-23270175 retained_intron
  ENST00000487890 GPNMB-006 23246768-23256910 processed_transcript
  ENST00000492512 GPNMB-005 23250713-23254312 retained_intron
  ENST00000492858 GPNMB-014 23236008-23257043 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000258733ENST00000381990ENST00000409458ENST00000463011ENST00000465673ENST00000468723ENST00000470994ENST00000478451ENST00000479625ENST00000487890ENST00000492512
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000258733 N/A 0.196±0.00 N/A N/A 0.244±0.21
ENST00000381990 0.126±0.00 0.079±0.05 0.163±0.00 0.163±0.00 0.234±0.41
ENST00000409458 0.111±0.00 0.068±0.03 N/A N/A 0.119±0.13
ENST00000463011 N/A 0.459±0.21 N/A 0.546±0.00 N/A
ENST00000465673 N/A 0.030±0.00 N/A N/A 0.127±0.02
ENST00000468723 N/A 0.258±0.14 N/A N/A 0.169±0.07
ENST00000470994 N/A N/A N/A N/A 0.172±0.10
ENST00000478451 N/A 0.098±0.00 N/A N/A 0.103±0.00
ENST00000479625 0.428±0.00 N/A N/A N/A 0.041±0.00
ENST00000487890 N/A 0.140±0.00 N/A N/A N/A
ENST00000492512 N/A 0.149±0.00 N/A 0.362±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00059M CIL_00059M_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0005178 IEA integrin binding
GO:0005887 IEA integral component of plasma membrane
GO:0007155 IEA cell adhesion
GO:0008201 IEA heparin binding
GO:0008285 TAS negative regulation of cell proliferation
GO:0016021 TAS integral component of membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0030282 IEA bone mineralization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062688 gpnmb protein_coding Danio_rerio
ENSMUSG00000029816 Gpnmb protein_coding Mus_musculus

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