ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sodium channel, voltage-gated, type VII, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136546 SCN7A 9606 - 2:166403573-166494247 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000409855 SCN7A-001 166403573-166486968 protein_coding
  ENST00000419992 SCN7A-002 166432321-166494247 protein_coding
  ENST00000424326 SCN7A-003 166405513-166486968 nonsense_mediated_decay
  ENST00000441411 SCN7A-004 166456953-166494205 protein_coding
  ENST00000497562 SCN7A-005 166461755-166465526 retained_intron
  ENST00000619410 SCN7A-201 166403573-166486971 protein_coding
  ENST00000621965 SCN7A-202 166403573-166486971 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000424326ENST00000497562
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000424326 N/A N/A N/A 0.003±0.00
ENST00000497562 0.072±0.00 0.084±0.04 0.128±0.00 0.063±0.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006CV CIL_0006CV_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 IEA:IBA voltage-gated sodium channel activity
GO:0005272 IEA sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0006936 IEA muscle contraction
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA:IBA sodium ion transmembrane transport
GO:0055078 IEA sodium ion homeostasis
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential
GO:0097386 IEA glial cell projection

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062744 scn1lab protein_coding Danio_rerio
ENSMUSG00000034810 Scn7a protein_coding Mus_musculus

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