ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: doublesex and mab-3 related transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137090 DMRT1 9606 + 9:841690-969090 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000382276 DMRT1-001 841690-969090 protein_coding
  ENST00000564322 DMRT1-003 841690-894985 retained_intron
  ENST00000569227 DMRT1-002 842714-968515 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000382276ENST00000564322ENST00000569227
Transcript ID BECs HAoEC HUVEC
ENST00000382276 0.040±0.00 0.273±0.17 0.086±0.02
ENST00000564322 0.097±0.00 0.035±0.01 N/A
ENST00000569227 N/A 0.064±0.06 0.077±0.05

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006YF CIL_0006YF_0002 CGP
CIL_0008UR CIL_0008UR_0001 VISTA
CIL_0008NH CIL_0008NH_0001 VISTA
CIL_0006Y7 CIL_0006Y7_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IEA cell morphogenesis
GO:0000987 ISS core promoter proximal region sequence-specific DNA binding
GO:0002176 ISS male germ cell proliferation
GO:0003006 IEA developmental process involved in reproduction
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007283 IEA spermatogenesis
GO:0008354 IEA germ cell migration
GO:0008584 IEA male gonad development
GO:0030238 ISS male sex determination
GO:0035556 IEA intracellular signal transduction
GO:0042803 IEA protein homodimerization activity
GO:0043565 IEA sequence-specific DNA binding
GO:0045835 ISS negative regulation of meiosis
GO:0045840 ISS positive regulation of mitosis
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046661 ISS male sex differentiation
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048599 IEA oocyte development
GO:0060008 ISS Sertoli cell differentiation
GO:0060009 IEA Sertoli cell development
GO:0060903 IEA positive regulation of meiosis I
GO:1900107 IEA regulation of nodal signaling pathway
GO:2000020 IEA positive regulation of male gonad development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007349 dmrt1 protein_coding Danio_rerio
ENSMUSG00000024837 Dmrt1 protein_coding Mus_musculus

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