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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein phosphatase, Mg2+/Mn2+ dependent, 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138032 PPM1B 9606 + 2:44167969-44244384 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282412 PPM1B-001 44168877-44231472 protein_coding
  ENST00000345249 PPM1B-003 44168910-44231472 protein_coding
  ENST00000378540 PPM1B-007 44168877-44244384 processed_transcript
  ENST00000378551 PPM1B-002 44168877-44234646 protein_coding
  ENST00000409432 PPM1B-004 44168877-44231471 protein_coding
  ENST00000409473 PPM1B-011 44201186-44218537 protein_coding
  ENST00000409486 PPM1B-006 44168877-44209432 retained_intron
  ENST00000419807 PPM1B-005 44167969-44218537 protein_coding
  ENST00000459690 PPM1B-010 44201946-44232721 processed_transcript
  ENST00000487286 PPM1B-009 44202017-44244383 processed_transcript
  ENST00000488866 PPM1B-012 44217822-44219203 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000282412ENST00000345249ENST00000378540ENST00000378551ENST00000409432ENST00000409473ENST00000409486ENST00000459690ENST00000487286
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000282412 N/A 2.962±1.49 N/A 4.271±0.00 3.666±1.87
ENST00000345249 1.620±0.01 N/A 8.772±0.00 N/A 2.860±0.00
ENST00000378540 N/A 1.995±0.00 N/A N/A 0.301±0.00
ENST00000378551 1.578±0.00 1.689±0.44 0.900±0.00 2.448±0.00 2.049±1.52
ENST00000409432 N/A 0.894±0.00 N/A N/A N/A
ENST00000409473 N/A 5.331±1.69 N/A 6.639±0.00 3.849±0.50
ENST00000409486 N/A 3.177±0.00 N/A N/A 2.084±1.28
ENST00000459690 N/A N/A N/A N/A 2.038±1.75
ENST00000487286 2.615±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001XM CIL_0001XM_0001 CGP
CIL_0004BC CIL_0004BC_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0003824 IEA catalytic activity
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 IEA:IDA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005829 ISS cytosol
GO:0006470 IEA:IMP protein dephosphorylation
GO:0006499 ISS N-terminal protein myristoylation
GO:0016020 ISS membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030145 IEA manganese ion binding
GO:0032688 IMP negative regulation of interferon-beta production
GO:0035970 IDA peptidyl-threonine dephosphorylation
GO:0042347 IMP negative regulation of NF-kappaB import into nucleus
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050687 IMP negative regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011496 ppm1bb protein_coding Danio_rerio
ENSMUSG00000061130 Ppm1b protein_coding Mus_musculus

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