ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: polyribonucleotide nucleotidyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138035 PNPT1 9606 - 2:55634063-55693910 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260604 PNPT1-004 55635094-55693842 nonsense_mediated_decay
  ENST00000415374 PNPT1-007 55634569-55693823 nonsense_mediated_decay
  ENST00000415489 PNPT1-008 55647401-55671368 nonsense_mediated_decay
  ENST00000429805 PNPT1-003 55679682-55693863 nonsense_mediated_decay
  ENST00000447944 PNPT1-001 55634265-55693910 protein_coding
  ENST00000481066 PNPT1-005 55636370-55647382 retained_intron
  ENST00000619878 PNPT1-201 55634063-55693910 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000260604ENST00000415374ENST00000429805ENST00000447944ENST00000481066ENST00000619878
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000260604 N/A 1.603±0.30 N/A 3.879±0.00 1.068±0.83
ENST00000415374 N/A 6.115±1.42 N/A 14.521±0.00 4.416±3.99
ENST00000429805 N/A N/A N/A N/A 5.157±2.93
ENST00000447944 N/A 1.522±0.55 N/A N/A 2.820±1.56
ENST00000481066 N/A N/A 3.045±0.00 N/A 1.137±0.29
ENST00000619878 1.214±0.12 1.327±0.29 2.761±0.00 5.383±0.00 1.062±0.46

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 IDA:IEA 3'-5'-exoribonuclease activity
GO:0000957 IDA mitochondrial RNA catabolic process
GO:0000958 IDA mitochondrial mRNA catabolic process
GO:0000962 IDA positive regulation of mitochondrial RNA catabolic process
GO:0000964 IMP mitochondrial RNA 5'-end processing
GO:0000965 IMP mitochondrial RNA 3'-end processing
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0004654 IEA polyribonucleotide nucleotidyltransferase activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005758 IDA mitochondrial intermembrane space
GO:0006396 IEA RNA processing
GO:0006401 IDA RNA catabolic process
GO:0006402 IEA mRNA catabolic process
GO:0008266 IDA poly(U) RNA binding
GO:0016020 IEA membrane
GO:0034046 IDA poly(G) binding
GO:0034599 IDA cellular response to oxidative stress
GO:0035198 IDA miRNA binding
GO:0035458 IDA cellular response to interferon-beta
GO:0035927 IDA RNA import into mitochondrion
GO:0035928 IDA rRNA import into mitochondrion
GO:0043457 ISS regulation of cellular respiration
GO:0043631 IDA RNA polyadenylation
GO:0044822 IDA poly(A) RNA binding
GO:0045025 IDA mitochondrial degradosome
GO:0045926 IDA negative regulation of growth
GO:0051260 IDA protein homooligomerization
GO:0061014 IMP positive regulation of mRNA catabolic process
GO:0070207 IDA protein homotrimerization
GO:0070584 ISS mitochondrion morphogenesis
GO:0071042 IDA nuclear polyadenylation-dependent mRNA catabolic process
GO:0071850 IDA mitotic cell cycle arrest
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:0097222 IMP mitochondrial mRNA polyadenylation
GO:2000627 IDA positive regulation of miRNA catabolic process
GO:2000772 IDA regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000020464 Pnpt1 protein_coding Mus_musculus

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