ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: aldehyde oxidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138356 AOX1 9606 + 2:200585868-200677064 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260930 AOX1-007 200660037-200670650 protein_coding
  ENST00000374700 AOX1-001 200585868-200671495 protein_coding
  ENST00000439380 AOX1-008 200662907-200677064 protein_coding
  ENST00000454629 AOX1-004 200588174-200603297 protein_coding
  ENST00000465297 AOX1-002 200609220-200670872 processed_transcript
  ENST00000472553 AOX1-006 200638132-200642803 retained_intron
  ENST00000485106 AOX1-003 200609243-200671136 processed_transcript
  ENST00000485965 AOX1-005 200609209-200613967 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000374700ENST00000465297ENST00000472553ENST00000485106ENST00000485965
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000374700 0.154±0.00 0.390±0.19 0.722±0.00 7.439±0.00 0.056±0.04
ENST00000465297 N/A 0.469±0.14 N/A 7.414±0.00 0.123±0.18
ENST00000472553 N/A N/A N/A N/A 0.225±0.10
ENST00000485106 N/A 0.344±0.08 N/A N/A 0.049±0.04
ENST00000485965 N/A N/A N/A N/A 0.234±0.25

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002B0 CIL_0002B0_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004031 TAS aldehyde oxidase activity
GO:0004854 TAS xanthine dehydrogenase activity
GO:0005506 IEA iron ion binding
GO:0005829 TAS cytosol
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006954 TAS inflammatory response
GO:0008762 IEA UDP-N-acetylmuramate dehydrogenase activity
GO:0009055 IEA electron carrier activity
GO:0016491 IEA oxidoreductase activity
GO:0016614 IEA oxidoreductase activity, acting on CH-OH group of donors
GO:0042816 TAS vitamin B6 metabolic process
GO:0043546 IEA molybdopterin cofactor binding
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0051287 IEA NAD binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0072593 TAS reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020054 aox1 protein_coding Danio_rerio
ENSMUSG00000063558 Aox1 protein_coding Mus_musculus

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