ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: abl-interactor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138443 ABI2 9606 + 2:203328219-203447723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261016 ABI2-201 203328239-203432172 protein_coding
  ENST00000261017 ABI2-002 203328280-203432173 protein_coding
  ENST00000261018 ABI2-202 203328239-203432172 protein_coding
  ENST00000295851 ABI2-001 203328219-203447723 protein_coding
  ENST00000376135 ABI2-015 203328459-203383296 processed_transcript
  ENST00000411547 ABI2-016 203380226-203402677 processed_transcript
  ENST00000413635 ABI2-011 203328395-203376132 nonsense_mediated_decay
  ENST00000416001 ABI2-003 203328391-203427569 nonsense_mediated_decay
  ENST00000416396 ABI2-021 203394748-203427219 processed_transcript
  ENST00000417864 ABI2-006 203328407-203427269 protein_coding
  ENST00000422511 ABI2-007 203328484-203428596 protein_coding
  ENST00000422719 ABI2-017 203380358-203416972 processed_transcript
  ENST00000424558 ABI2-005 203328395-203427948 protein_coding
  ENST00000425253 ABI2-023 203328394-203366957 nonsense_mediated_decay
  ENST00000430418 ABI2-004 203328392-203427528 protein_coding
  ENST00000430574 ABI2-019 203380275-203416983 processed_transcript
  ENST00000431886 ABI2-013 203328399-203380277 nonsense_mediated_decay
  ENST00000441061 ABI2-008 203328336-203427528 nonsense_mediated_decay
  ENST00000444584 ABI2-014 203328405-203380273 nonsense_mediated_decay
  ENST00000447762 ABI2-024 203328282-203380306 nonsense_mediated_decay
  ENST00000451591 ABI2-018 203380308-203402734 protein_coding
  ENST00000454023 ABI2-020 203391044-203427411 protein_coding
  ENST00000464761 ABI2-022 203402706-203436883 processed_transcript
  ENST00000494215 ABI2-012 203328458-203367419 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000261016ENST00000261017ENST00000295851ENST00000416001ENST00000441061ENST00000454023
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000261016 1.267±0.00 N/A N/A N/A 0.876±0.00
ENST00000261017 2.393±0.13 7.743±1.80 5.803±0.00 12.546±0.00 6.944±3.00
ENST00000295851 N/A N/A N/A N/A 0.448±0.00
ENST00000416001 8.715±0.00 N/A N/A N/A N/A
ENST00000441061 N/A N/A N/A N/A 4.371±0.56
ENST00000454023 N/A N/A N/A N/A 11.865±2.18

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000JP CIL_0000JP_0002 CGP
CIL_0000JQ CIL_0000JQ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 TAS DNA binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0005913 IEA cell-cell adherens junction
GO:0006928 IDA cellular component movement
GO:0007010 TAS cytoskeleton organization
GO:0007611 IEA learning or memory
GO:0008093 TAS cytoskeletal adaptor activity
GO:0008154 NAS actin polymerization or depolymerization
GO:0016358 IEA dendrite development
GO:0016477 TAS cell migration
GO:0016601 IDA Rac protein signal transduction
GO:0017124 IPI SH3 domain binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019900 NAS kinase binding
GO:0030027 IDA lamellipodium
GO:0030175 IDA filopodium
GO:0030425 IEA dendrite
GO:0031209 IDA SCAR complex
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032403 IDA protein complex binding
GO:0043010 IEA camera-type eye development
GO:0048365 IDA Rac GTPase binding
GO:0070064 IPI proline-rich region binding
GO:2000601 IDA positive regulation of Arp2/3 complex-mediated actin nucleation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014875 abi2b protein_coding Danio_rerio
ENSDARG00000058207 abi2a protein_coding Danio_rerio
ENSMUSG00000026782 Abi2 protein_coding Mus_musculus

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