ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 40 (iron-regulated transporter), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138449 SLC40A1 9606 - 2:189560579-189583758 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261024 SLC40A1-001 189560579-189580887 protein_coding
  ENST00000418714 SLC40A1-008 189575161-189580783 processed_transcript
  ENST00000427241 SLC40A1-002 189565513-189583758 protein_coding
  ENST00000427419 SLC40A1-003 189579848-189582022 protein_coding
  ENST00000440626 SLC40A1-005 189579848-189583402 protein_coding
  ENST00000455320 SLC40A1-004 189575266-189582031 protein_coding
  ENST00000479598 SLC40A1-006 189572521-189580741 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000261024ENST00000418714
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000261024 0.493±0.00 6.976±3.99 3.468±0.00 9.938±0.00 7.124±7.03
ENST00000418714 N/A N/A N/A N/A 5.249±2.09

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002260 IEA lymphocyte homeostasis
GO:0003158 IEA endothelium development
GO:0005381 IMP:IEA iron ion transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005737 TAS cytoplasm
GO:0005771 IEA multivesicular body
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006826 IEA iron ion transport
GO:0006879 IMP cellular iron ion homeostasis
GO:0008021 IEA synaptic vesicle
GO:0009653 TAS anatomical structure morphogenesis
GO:0016021 IEA:TAS integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0034395 IEA regulation of transcription from RNA polymerase II promoter in response to iron
GO:0034755 IEA:IMP iron ion transmembrane transport
GO:0043066 IEA negative regulation of apoptotic process
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048536 IEA spleen development
GO:0055085 TAS transmembrane transport
GO:0060345 IEA spleen trabecula formation
GO:0060586 IEA multicellular organismal iron ion homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000241 slc40a1 protein_coding Danio_rerio
ENSMUSG00000025993 Slc40a1 protein_coding Mus_musculus

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