ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: signal peptide peptidase like 2A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138600 SPPL2A 9606 - 15:50702266-50765808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261854 SPPL2A-001 50702266-50765808 protein_coding
  ENST00000558146 SPPL2A-006 50722173-50725519 retained_intron
  ENST00000558414 SPPL2A-003 50747504-50764561 protein_coding
  ENST00000558934 SPPL2A-004 50707448-50747531 protein_coding
  ENST00000559293 SPPL2A-005 50722141-50726327 processed_transcript
  ENST00000559527 SPPL2A-007 50725916-50747508 retained_intron
  ENST00000560288 SPPL2A-002 50747997-50765709 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000261854ENST00000558414ENST00000558934ENST00000560288
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000261854 1.501±0.00 2.386±1.71 N/A 3.609±0.00 3.625±2.69
ENST00000558414 N/A 11.432±4.72 N/A 27.552±0.00 30.286±7.62
ENST00000558934 16.481±0.04 9.320±3.57 11.922±0.00 26.104±0.00 13.605±8.88
ENST00000560288 N/A N/A N/A N/A 9.132±4.79

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002DX CIL_0002DX_0001 CGP
CIL_00024D CIL_00024D_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004190 IEA aspartic-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005886 IEA plasma membrane
GO:0006508 IEA proteolysis
GO:0006509 IDA membrane protein ectodomain proteolysis
GO:0016021 IEA integral component of membrane
GO:0030660 IDA Golgi-associated vesicle membrane
GO:0031293 IDA membrane protein intracellular domain proteolysis
GO:0031902 IEA late endosome membrane
GO:0042803 IDA protein homodimerization activity
GO:0050776 IMP regulation of immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0071458 IDA integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 IDA integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027366 Sppl2a protein_coding Mus_musculus

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