ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138623 SEMA7A 9606 - 15:74409289-74434467 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261918 SEMA7A-001 74409289-74434467 protein_coding
  ENST00000542748 SEMA7A-201 74409290-74433660 protein_coding
  ENST00000543145 SEMA7A-002 74410316-74433955 protein_coding
  ENST00000567345 SEMA7A-005 74416639-74433704 protein_coding
  ENST00000569617 SEMA7A-004 74410968-74411639 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000261918ENST00000542748ENST00000543145ENST00000567345ENST00000569617
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000261918 0.053±0.00 0.089±0.04 N/A N/A 0.647±1.07
ENST00000542748 0.630±0.13 1.717±1.70 0.325±0.00 3.917±0.00 1.491±1.44
ENST00000543145 N/A 1.024±0.85 N/A 1.972±0.00 1.215±0.94
ENST00000567345 N/A 0.131±0.00 N/A N/A 0.256±0.21
ENST00000569617 N/A N/A N/A N/A 0.026±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007UD CIL_0007UD_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IDA osteoblast differentiation
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004872 IEA receptor activity
GO:0005178 IEA integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0007229 IDA integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0007411 TAS axon guidance
GO:0009897 ISS external side of plasma membrane
GO:0016020 IDA:IEA membrane
GO:0021988 IEA olfactory lobe development
GO:0031175 IEA neuron projection development
GO:0031225 IEA anchored component of membrane
GO:0045773 IDA positive regulation of axon extension
GO:0048675 IEA axon extension
GO:0050727 ISS regulation of inflammatory response
GO:0060907 ISS positive regulation of macrophage cytokine production
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078707 sema7a protein_coding Danio_rerio
ENSMUSG00000038264 Sema7a protein_coding Mus_musculus

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