ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138642 HERC6 9606 + 4:88378739-88443111 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264346 HERC6-001 88378863-88443111 protein_coding
  ENST00000273960 HERC6-201 88378739-88443096 protein_coding
  ENST00000380265 HERC6-003 88378739-88443097 protein_coding
  ENST00000502870 HERC6-006 88379064-88390878 protein_coding
  ENST00000504905 HERC6-002 88378911-88390732 nonsense_mediated_decay
  ENST00000506714 HERC6-004 88378991-88399769 retained_intron
  ENST00000506842 HERC6-009 88439845-88440640 retained_intron
  ENST00000515365 HERC6-005 88390820-88405025 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000264346ENST00000273960ENST00000380265ENST00000506714ENST00000515365
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000264346 0.153±0.00 0.461±0.17 N/A 12.074±0.00 0.787±0.48
ENST00000273960 0.823±0.07 0.134±0.00 0.948±0.00 N/A 0.231±0.08
ENST00000380265 N/A 0.340±0.00 N/A 2.171±0.00 0.475±0.24
ENST00000506714 N/A N/A N/A N/A 0.062±0.00
ENST00000515365 N/A 0.770±0.29 N/A N/A 0.373±0.10

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000KK CIL_0000KK_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0004842 IBA:IEA ubiquitin-protein transferase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0016874 IEA ligase activity
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029798 Herc6 protein_coding Mus_musculus

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