ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: TOPBP1-interacting checkpoint and replication regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140534 TICRR 9606 + 15:89575482-89631056 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268138 TICRR-001 89575482-89628023 protein_coding
  ENST00000560985 TICRR-003 89575587-89628012 protein_coding
  ENST00000561095 TICRR-002 89625400-89631056 nonsense_mediated_decay

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000268138ENST00000560985ENST00000561095
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000268138 0.875±0.00 1.033±0.54 0.644±0.00 1.051±0.63
ENST00000560985 0.780±0.00 0.884±0.33 N/A 0.429±0.25
ENST00000561095 N/A N/A N/A 1.340±0.60

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00011D CIL_00011D_0001 CGP
CIL_00008C CIL_00008C_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000075 ISS cell cycle checkpoint
GO:0001731 ISS formation of translation preinitiation complex
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006260 ISS DNA replication
GO:0006281 ISS DNA repair
GO:0010212 ISS response to ionizing radiation
GO:0030174 IMP regulation of DNA-dependent DNA replication initiation
GO:0033314 ISS mitotic DNA replication checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000046591 Ticrr protein_coding Mus_musculus

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