ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140557 ST8SIA2 9606 + 15:92393828-92468728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268164 ST8SIA2-001 92393828-92468728 protein_coding
  ENST00000539113 ST8SIA2-002 92394041-92464385 protein_coding
  ENST00000555434 ST8SIA2-003 92394065-92464384 protein_coding
  ENST00000556382 ST8SIA2-004 92434316-92445124 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000268164ENST00000539113ENST00000555434ENST00000556382
Transcript ID BECs HAoEC HUVEC
ENST00000268164 0.017±0.01 0.006±0.00 0.023±0.03
ENST00000539113 N/A 0.030±0.00 0.072±0.03
ENST00000555434 N/A N/A 0.130±0.07
ENST00000556382 0.063±0.00 0.048±0.00 0.145±0.08

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001574 IDA ganglioside biosynthetic process
GO:0003828 IDA alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0005769 IEA early endosome
GO:0005975 TAS carbohydrate metabolic process
GO:0006464 TAS cellular protein modification process
GO:0006486 IDA:IEA protein glycosylation
GO:0006491 IDA N-glycan processing
GO:0007399 TAS nervous system development
GO:0007411 TAS axon guidance
GO:0008373 IEA sialyltransferase activity
GO:0009311 IDA oligosaccharide metabolic process
GO:0018279 TAS protein N-linked glycosylation via asparagine
GO:0030173 IEA integral component of Golgi membrane
GO:0033691 IC sialic acid binding
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0055037 IEA recycling endosome
GO:0097503 IEA sialylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018788 st8sia2 protein_coding Danio_rerio
ENSMUSG00000025789 St8sia2 protein_coding Mus_musculus

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