ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: poly(A)-specific ribonuclease
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140694 PARN 9606 - 16:14435701-14632728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341484 PARN-002 14436605-14630276 protein_coding
  ENST00000420015 PARN-003 14436273-14630259 protein_coding
  ENST00000437198 PARN-001 14435701-14630267 protein_coding
  ENST00000538472 PARN-005 14599935-14630218 nonsense_mediated_decay
  ENST00000539279 PARN-004 14436668-14630238 protein_coding
  ENST00000562715 PARN-012 14576072-14584791 processed_transcript
  ENST00000562896 PARN-006 14627176-14632728 protein_coding
  ENST00000563155 PARN-009 14608107-14610699 retained_intron
  ENST00000563641 PARN-007 14586318-14630260 nonsense_mediated_decay
  ENST00000563697 PARN-013 14555686-14584760 processed_transcript
  ENST00000564113 PARN-011 14555654-14592077 processed_transcript
  ENST00000564882 PARN-014 14446957-14501689 processed_transcript
  ENST00000564904 PARN-015 14482638-14565075 processed_transcript
  ENST00000566021 PARN-008 14610665-14630251 processed_transcript
  ENST00000569444 PARN-010 14555654-14610743 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHUVECENST00000341484ENST00000437198ENST00000563641ENST00000566021ENST00000569444
Transcript ID HAoEC HHSEC HUVEC
ENST00000341484 2.646±0.25 N/A 0.965±0.27
ENST00000437198 4.652±1.85 1.673±0.00 3.738±2.38
ENST00000563641 N/A N/A 6.422±0.00
ENST00000566021 N/A N/A 5.527±0.77
ENST00000569444 7.530±0.52 N/A 0.331±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007DW CIL_0007DW_0001 CGP
CIL_0007DV CIL_0007DV_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000184 IMP nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0003730 TAS mRNA 3'-UTR binding
GO:0004518 TAS nuclease activity
GO:0004535 TAS:IEA poly(A)-specific ribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 TAS:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006402 IEA mRNA catabolic process
GO:0007292 TAS female gamete generation
GO:0009451 TAS RNA modification
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019901 IPI protein kinase binding
GO:0044822 IDA poly(A) RNA binding
GO:0046872 IEA metal ion binding
GO:0090305 TAS nucleic acid phosphodiester bond hydrolysis
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000022685 Parn protein_coding Mus_musculus

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