ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: myosin light chain kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140795 MYLK3 9606 - 16:46706979-46790407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000394809 MYLK3-001 46706979-46748309 protein_coding
  ENST00000536476 MYLK3-003 46707666-46763246 protein_coding
  ENST00000562104 MYLK3-006 46707692-46711790 processed_transcript
  ENST00000564731 MYLK3-002 46725776-46738137 retained_intron
  ENST00000565182 MYLK3-007 46707668-46710987 retained_intron
  ENST00000569810 MYLK3-004 46738038-46790407 processed_transcript
  ENST00000569844 MYLK3-005 46727238-46729937 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000394809ENST00000536476ENST00000564731ENST00000565182ENST00000569844
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000394809 N/A 0.020±0.01 N/A 0.010±0.00
ENST00000536476 N/A N/A N/A 0.022±0.01
ENST00000564731 0.069±0.00 0.177±0.05 0.099±0.00 0.066±0.07
ENST00000565182 N/A 0.153±0.00 N/A 0.046±0.00
ENST00000569844 N/A N/A N/A 0.046±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00044W CIL_00044W_0002 CGP
CIL_00044Z CIL_00044Z_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002528 IMP regulation of vascular permeability involved in acute inflammatory response
GO:0004672 IEA protein kinase activity
GO:0004683 ISS calmodulin-dependent protein kinase activity
GO:0004687 ISS myosin light chain kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005737 ISS cytoplasm
GO:0005829 ISS cytosol
GO:0006468 ISS:IEA protein phosphorylation
GO:0015629 IEA actin cytoskeleton
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0045214 ISS sarcomere organization
GO:0048769 ISS sarcomerogenesis
GO:0055003 ISS cardiac myofibril assembly
GO:0060298 ISS positive regulation of sarcomere organization
GO:0071347 IMP cellular response to interleukin-1

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076348 mylk3 protein_coding Danio_rerio
ENSMUSG00000031698 Mylk3 protein_coding Mus_musculus

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