ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140873 ADAMTS18 9606 - 16:77247813-77435114 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282849 ADAMTS18-001 77282128-77435114 protein_coding
  ENST00000449265 ADAMTS18-002 77355951-77435034 nonsense_mediated_decay
  ENST00000562332 ADAMTS18-011 77247813-77289359 protein_coding
  ENST00000562345 ADAMTS18-009 77364352-77431587 protein_coding
  ENST00000564369 ADAMTS18-005 77367571-77434521 processed_transcript
  ENST00000567121 ADAMTS18-006 77367483-77432448 processed_transcript
  ENST00000567914 ADAMTS18-008 77367437-77431633 retained_intron
  ENST00000568393 ADAMTS18-010 77300039-77321136 retained_intron
  ENST00000569309 ADAMTS18-007 77367610-77431746 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000282849
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000282849 0.253±0.00 1.264±0.90 5.669±0.00 7.568±6.95

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003OG CIL_0003OG_0001 CGP
CIL_0003OF CIL_0003OF_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001654 IMP eye development
GO:0004222 IEA metalloendopeptidase activity
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008233 IEA peptidase activity
GO:0008270 IEA zinc ion binding
GO:0031012 IEA extracellular matrix
GO:0090331 IDA negative regulation of platelet aggregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001999 adamts18 protein_coding Danio_rerio
ENSMUSG00000053399 Adamts18 protein_coding Mus_musculus

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