Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
            );
$key = 'cake_dev_eng'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = array(
	(int) 0 => 'diffexp',
	(int) 1 => 'experiment',
	(int) 2 => 'expressed_transcripts',
	(int) 3 => 'genes',
	(int) 4 => 'go_annotations',
	(int) 5 => 'homologues',
	(int) 6 => 'repeats',
	(int) 7 => 'study',
	(int) 8 => 'synonyms',
	(int) 9 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_genes' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_genes'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_genes' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_genes'
$value = array(
	'id' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 32,
		'key' => 'primary',
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_version' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'tax_id' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'assembly' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'chromosome' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'strand' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'start' => array(
		'type' => 'integer',
		'null' => false,
		'default' => null,
		'length' => (int) 11,
		'unsigned' => false
	),
	'end' => array(
		'type' => 'integer',
		'null' => false,
		'default' => null,
		'length' => (int) 11,
		'unsigned' => false
	),
	'gene_name' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_source' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_biotype' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'annotation_version' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_description' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	)
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

• HOME
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Gene Info
Description:	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000141404	GNAL	9606	+	18:11688956-11885685	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000269162		GNAL-004	11751508-11881410	protein_coding
	ENST00000334049		GNAL-001	11688956-11885685	protein_coding
	ENST00000423027		GNAL-002	11752113-11881923	protein_coding
	ENST00000535121		GNAL-005	11751472-11881135	protein_coding
	ENST00000585590		GNAL-007	11689690-11702291	processed_transcript
	ENST00000585642		GNAL-008	11752806-11868584	protein_coding
	ENST00000586926		GNAL-011	11872301-11874403	protein_coding
	ENST00000590228		GNAL-009	11753548-11868586	protein_coding
	ENST00000590972		GNAL-010	11752884-11833667	processed_transcript
	ENST00000602628		GNAL-006	11857440-11881172	protein_coding

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID HAoEC HUVEC ENST00000269162 N/A 0.224±0.00 ENST00000334049 0.311±0.00 0.328±0.17

Conserved Regions
Not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001664	IBA	G-protein coupled receptor binding
GO:0001975	IEA	response to amphetamine
GO:0003924	IEA:IBA	GTPase activity
GO:0004871	IEA:IBA	signal transducer activity
GO:0005525	IEA	GTP binding
GO:0005834	IBA	heterotrimeric G-protein complex
GO:0005886	TAS	plasma membrane
GO:0006184	IEA	GTP catabolic process
GO:0007165	TAS:IEA	signal transduction
GO:0007186	IEA	G-protein coupled receptor signaling pathway
GO:0007189	TAS	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190	IEA	activation of adenylate cyclase activity
GO:0007191	IBA	adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193	TAS	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007268	TAS	synaptic transmission
GO:0007608	IBA	sensory perception of smell
GO:0019001	IEA	guanyl nucleotide binding
GO:0031000	IEA	response to caffeine
GO:0031683	IEA:IBA	G-protein beta/gamma-subunit complex binding
GO:0046872	IEA	metal ion binding
GO:0070062	IDA	extracellular vesicular exosome

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000075850	gnal2		TR_V_gene	Danio_rerio
ENSMUSG00000024524	Gnal		protein_coding	Mus_musculus

Loading

Warning (512): _cake_core_ cache was unable to write 'file_map' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
            );
$key = 'file_map'
$value = array(
	'Configure' => '/var/www/angiogenes/lib/Cake/Core/Configure.php',
	'Hash' => '/var/www/angiogenes/lib/Cake/Utility/Hash.php',
	'Cache' => '/var/www/angiogenes/lib/Cake/Cache/Cache.php',
	'FileEngine' => '/var/www/angiogenes/lib/Cake/Cache/Engine/FileEngine.php',
	'CacheEngine' => '/var/www/angiogenes/lib/Cake/Cache/CacheEngine.php',
	'Inflector' => '/var/www/angiogenes/lib/Cake/Utility/Inflector.php',
	'ErrorHandler' => '/var/www/angiogenes/lib/Cake/Error/ErrorHandler.php',
	'CakePlugin' => '/var/www/angiogenes/lib/Cake/Core/CakePlugin.php',
	'CakeLog' => '/var/www/angiogenes/lib/Cake/Log/CakeLog.php',
	'LogEngineCollection' => '/var/www/angiogenes/lib/Cake/Log/LogEngineCollection.php',
	'ObjectCollection' => '/var/www/angiogenes/lib/Cake/Utility/ObjectCollection.php',
	'FileLog' => '/var/www/angiogenes/lib/Cake/Log/Engine/FileLog.php',
	'BaseLog' => '/var/www/angiogenes/lib/Cake/Log/Engine/BaseLog.php',
	'CakeLogInterface' => '/var/www/angiogenes/lib/Cake/Log/CakeLogInterface.php',
	'Debugger' => '/var/www/angiogenes/lib/Cake/Utility/Debugger.php',
	'String' => '/var/www/angiogenes/lib/Cake/Utility/String.php',
	'Dispatcher' => '/var/www/angiogenes/lib/Cake/Routing/Dispatcher.php',
	'CakeEventListener' => '/var/www/angiogenes/lib/Cake/Event/CakeEventListener.php',
	'CakeRequest' => '/var/www/angiogenes/lib/Cake/Network/CakeRequest.php',
	'CakeResponse' => '/var/www/angiogenes/lib/Cake/Network/CakeResponse.php',
	'CakeEvent' => '/var/www/angiogenes/lib/Cake/Event/CakeEvent.php',
	'CakeEventManager' => '/var/www/angiogenes/lib/Cake/Event/CakeEventManager.php',
	'AssetDispatcher' => '/var/www/angiogenes/lib/Cake/Routing/Filter/AssetDispatcher.php',
	'DispatcherFilter' => '/var/www/angiogenes/lib/Cake/Routing/DispatcherFilter.php',
	'CacheDispatcher' => '/var/www/angiogenes/lib/Cake/Routing/Filter/CacheDispatcher.php',
	'Router' => '/var/www/angiogenes/lib/Cake/Routing/Router.php',
	'CakeRoute' => '/var/www/angiogenes/lib/Cake/Routing/Route/CakeRoute.php',
	'PluginShortRoute' => '/var/www/angiogenes/lib/Cake/Routing/Route/PluginShortRoute.php',
	'GeneController' => '/var/www/angiogenes/app/Controller/GeneController.php',
	'AppController' => '/var/www/angiogenes/app/Controller/AppController.php',
	'Controller' => '/var/www/angiogenes/lib/Cake/Controller/Controller.php',
	'Object' => '/var/www/angiogenes/lib/Cake/Core/Object.php',
	'ComponentCollection' => '/var/www/angiogenes/lib/Cake/Controller/ComponentCollection.php',
	'SessionComponent' => '/var/www/angiogenes/lib/Cake/Controller/Component/SessionComponent.php',
	'Component' => '/var/www/angiogenes/lib/Cake/Controller/Component.php',
	'RequestHandlerComponent' => '/var/www/angiogenes/lib/Cake/Controller/Component/RequestHandlerComponent.php',
	'ClassRegistry' => '/var/www/angiogenes/lib/Cake/Utility/ClassRegistry.php',
	'Gene' => '/var/www/angiogenes/app/Model/Gene.php',
	'AppModel' => '/var/www/angiogenes/app/Model/AppModel.php',
	'Model' => '/var/www/angiogenes/lib/Cake/Model/Model.php',
	'BehaviorCollection' => '/var/www/angiogenes/lib/Cake/Model/BehaviorCollection.php',
	'ConnectionManager' => '/var/www/angiogenes/lib/Cake/Model/ConnectionManager.php',
	'Mysql' => '/var/www/angiogenes/lib/Cake/Model/Datasource/Database/Mysql.php',
	'DboSource' => '/var/www/angiogenes/lib/Cake/Model/Datasource/DboSource.php',
	'DataSource' => '/var/www/angiogenes/lib/Cake/Model/Datasource/DataSource.php',
	'I18n' => '/var/www/angiogenes/lib/Cake/I18n/I18n.php',
	'L10n' => '/var/www/angiogenes/lib/Cake/I18n/L10n.php',
	'CakeSession' => '/var/www/angiogenes/lib/Cake/Model/Datasource/CakeSession.php',
	'View' => '/var/www/angiogenes/lib/Cake/View/View.php',
	'HelperCollection' => '/var/www/angiogenes/lib/Cake/View/HelperCollection.php',
	'ViewBlock' => '/var/www/angiogenes/lib/Cake/View/ViewBlock.php',
	'HtmlHelper' => '/var/www/angiogenes/lib/Cake/View/Helper/HtmlHelper.php',
	'AppHelper' => '/var/www/angiogenes/app/View/Helper/AppHelper.php',
	'Helper' => '/var/www/angiogenes/lib/Cake/View/Helper.php',
	'FormHelper' => '/var/www/angiogenes/lib/Cake/View/Helper/FormHelper.php',
	'SessionHelper' => '/var/www/angiogenes/lib/Cake/View/Helper/SessionHelper.php'
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

Warning (512): _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
            );
$key = 'method_cache'
$value = array(
	(int) 0 => false,
	'name' => array(
		'8e3e6ac3f0ef6fb8bcf1424a6423ed87' => '`angiogenes`',
		'4d0d73f550e4b0573d9cf666d63a0244' => '`genes`',
		'003d5968b53baeeb0cb27d56c4d447af' => '`Gene`.`id`',
		'f32f1dc049466870a2299961f0604112' => '`Gene`.`gene_version`',
		'433a39b330b04a021541e6fa89d80ffd' => '`Gene`.`tax_id`',
		'56705ff3488da428f13156180dbc9fbc' => '`Gene`.`assembly`',
		'b7d572bb36c8f0f2ecfe36921c14fbf3' => '`Gene`.`chromosome`',
		'edf6b12f8a40424f91fa0a40f0eab275' => '`Gene`.`strand`',
		'71d92ec0ad29837870abd0de3ae8addc' => '`Gene`.`start`',
		'62e43d606bf4cdae2d6694c62e19e7fa' => '`Gene`.`end`',
		'7043386674301bd31c5e629dfdadabd4' => '`Gene`.`gene_name`',
		'f1454297621ddcf07c418e47f67d3857' => '`Gene`.`gene_source`',
		'27d53785bfcd771f1901030b4bb87d02' => '`Gene`.`gene_biotype`',
		'b93574bf8a03f2d6f6486e920115e0d1' => '`Gene`.`annotation_version`',
		'1c4a3f5d90070e8ea1c62ca077df603e' => '`Gene`.`gene_description`',
		'8ca7a0c53312b8ae3cfa40a9d814adac' => '`Gene`'
	),
	'fields' => array(
		'47cba37bb7792f95f7499f6996d48351' => array(
			(int) 0 => '`Gene`.`id`',
			(int) 1 => '`Gene`.`gene_version`',
			(int) 2 => '`Gene`.`tax_id`',
			(int) 3 => '`Gene`.`assembly`',
			(int) 4 => '`Gene`.`chromosome`',
			(int) 5 => '`Gene`.`strand`',
			(int) 6 => '`Gene`.`start`',
			(int) 7 => '`Gene`.`end`',
			(int) 8 => '`Gene`.`gene_name`',
			(int) 9 => '`Gene`.`gene_source`',
			(int) 10 => '`Gene`.`gene_biotype`',
			(int) 11 => '`Gene`.`annotation_version`',
			(int) 12 => '`Gene`.`gene_description`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??