ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: misshapen-like kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141503 MINK1 9606 + 17:4833388-4898061 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000347992 MINK1-002 4833400-4898054 protein_coding
  ENST00000355280 MINK1-001 4833388-4898053 protein_coding
  ENST00000453408 MINK1-003 4833584-4897287 protein_coding
  ENST00000571207 MINK1-006 4884469-4898061 nonsense_mediated_decay
  ENST00000571526 MINK1-011 4893196-4893871 retained_intron
  ENST00000572304 MINK1-012 4893578-4894216 retained_intron
  ENST00000572330 MINK1-004 4833399-4897805 retained_intron
  ENST00000572629 MINK1-010 4892471-4893650 retained_intron
  ENST00000574453 MINK1-005 4833413-4898053 nonsense_mediated_decay
  ENST00000574871 MINK1-008 4894544-4898060 retained_intron
  ENST00000575511 MINK1-013 4894858-4895789 retained_intron
  ENST00000576037 MINK1-014 4896205-4897145 protein_coding
  ENST00000577021 MINK1-009 4833621-4885965 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000347992ENST00000355280ENST00000453408ENST00000571207ENST00000572330ENST00000574453ENST00000574871
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000347992 N/A 5.453±0.07 N/A N/A N/A
ENST00000355280 6.811±0.00 7.692±2.79 22.798±0.00 16.955±0.00 13.708±8.81
ENST00000453408 N/A 9.371±3.41 N/A N/A 8.091±4.03
ENST00000571207 3.938±0.00 N/A 13.103±0.00 N/A 7.719±2.93
ENST00000572330 N/A N/A N/A N/A 2.662±2.05
ENST00000574453 N/A N/A N/A N/A 1.617±0.41
ENST00000574871 N/A N/A N/A N/A 1.013±0.41

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001RG CIL_0001RG_0001 CGP
CIL_0001R8 CIL_0001R8_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001952 IMP regulation of cell-matrix adhesion
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006950 ISS response to stress
GO:0007254 TAS JNK cascade
GO:0007268 ISS synaptic transmission
GO:0007275 ISS multicellular organismal development
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0022407 IMP regulation of cell-cell adhesion
GO:0030054 IEA cell junction
GO:0030334 IMP regulation of cell migration
GO:0031532 IMP actin cytoskeleton reorganization
GO:0035556 ISS intracellular signal transduction
GO:0042995 IEA cell projection
GO:0045060 IEA negative thymic T cell selection
GO:0045211 IEA postsynaptic membrane
GO:0046330 IMP positive regulation of JNK cascade
GO:0046777 IDA protein autophosphorylation
GO:0048813 ISS dendrite morphogenesis
GO:0050790 IEA regulation of catalytic activity
GO:0070062 IDA extracellular vesicular exosome
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035360 mink1 protein_coding Danio_rerio
ENSMUSG00000020827 Mink1 protein_coding Mus_musculus

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