ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: heparan sulfate proteoglycan 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142798 HSPG2 9606 - 1:21822245-21937297 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374673 HSPG2-004 21887235-21888721 protein_coding
  ENST00000374676 HSPG2-010 21835409-21839006 protein_coding
  ENST00000374695 HSPG2-001 21822245-21937297 protein_coding
  ENST00000412328 HSPG2-003 21887233-21896310 protein_coding
  ENST00000426143 HSPG2-013 21833538-21835347 protein_coding
  ENST00000427897 HSPG2-008 21872859-21874706 protein_coding
  ENST00000439717 HSPG2-005 21889816-21896271 protein_coding
  ENST00000453796 HSPG2-015 21846196-21847958 protein_coding
  ENST00000469378 HSPG2-011 21833116-21833614 processed_transcript
  ENST00000471322 HSPG2-014 21835153-21836917 processed_transcript
  ENST00000480900 HSPG2-006 21877514-21879074 retained_intron
  ENST00000481644 HSPG2-012 21823301-21824266 processed_transcript
  ENST00000486901 HSPG2-002 21822245-21830713 processed_transcript
  ENST00000493940 HSPG2-009 21851311-21854656 processed_transcript
  ENST00000498495 HSPG2-007 21874478-21875208 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000374695ENST00000486901
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000374695 50.245±3.46 288.277±72.19 334.965±0.00 286.656±175.98
ENST00000486901 89.684±0.00 N/A N/A 173.618±6.41

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002WF CIL_0002WF_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001525 IEA angiogenesis
GO:0001958 IEA endochondral ossification
GO:0002062 IEA chondrocyte differentiation
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005604 IEA basement membrane
GO:0005605 IEA basal lamina
GO:0005615 IDA extracellular space
GO:0005796 TAS Golgi lumen
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0005975 TAS carbohydrate metabolic process
GO:0006024 TAS glycosaminoglycan biosynthetic process
GO:0006027 TAS glycosaminoglycan catabolic process
GO:0007420 IEA brain development
GO:0007603 TAS phototransduction, visible light
GO:0008022 IPI protein C-terminus binding
GO:0008104 IEA protein localization
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030204 TAS chondroitin sulfate metabolic process
GO:0031012 IDA extracellular matrix
GO:0042157 TAS lipoprotein metabolic process
GO:0043202 TAS lysosomal lumen
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0048704 IEA embryonic skeletal system morphogenesis
GO:0048738 IEA cardiac muscle tissue development
GO:0060351 IEA cartilage development involved in endochondral bone morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076564 hspg2 protein_coding Danio_rerio
ENSMUSG00000028763 Hspg2 protein_coding Mus_musculus

Loading