ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: metal response element binding transcription factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143033 MTF2 9606 + 1:93079235-93139081 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370298 MTF2-001 93079238-93139081 protein_coding
  ENST00000370303 MTF2-003 93079311-93137151 protein_coding
  ENST00000467953 MTF2-007 93110246-93137132 processed_transcript
  ENST00000468457 MTF2-010 93118345-93120274 retained_intron
  ENST00000471953 MTF2-002 93079310-93137089 processed_transcript
  ENST00000473430 MTF2-006 93079283-93119401 processed_transcript
  ENST00000474314 MTF2-011 93079270-93115492 processed_transcript
  ENST00000476037 MTF2-008 93120793-93136852 processed_transcript
  ENST00000487263 MTF2-009 93120799-93134459 processed_transcript
  ENST00000489480 MTF2-004 93128795-93137132 processed_transcript
  ENST00000494963 MTF2-005 93079296-93119338 processed_transcript
  ENST00000497976 MTF2-012 93110424-93133740 processed_transcript
  ENST00000540243 MTF2-201 93079235-93139079 protein_coding
  ENST00000545708 MTF2-202 93079235-93139079 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000370298ENST00000370303ENST00000467953ENST00000468457ENST00000473430ENST00000489480ENST00000497976ENST00000540243ENST00000545708
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000370298 N/A 2.176±1.95 N/A 3.474±1.75
ENST00000370303 N/A 2.179±0.71 3.366±0.00 2.916±1.18
ENST00000467953 N/A 1.399±0.64 3.294±0.00 2.941±0.88
ENST00000468457 N/A N/A N/A 2.976±0.00
ENST00000473430 N/A 3.008±0.00 N/A 5.967±3.68
ENST00000489480 2.044±0.00 N/A N/A N/A
ENST00000497976 N/A N/A N/A 5.180±0.00
ENST00000540243 N/A 0.938±0.52 N/A 1.724±0.00
ENST00000545708 N/A 1.068±0.20 N/A 1.762±0.67

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005ZP CIL_0005ZP_0001 CGP
CIL_0005ZQ CIL_0005ZQ_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007379 ISS segment specification
GO:0008270 IEA zinc ion binding
GO:0016568 IEA chromatin modification
GO:0019827 ISS stem cell maintenance
GO:0035064 IDA methylated histone binding
GO:0035098 ISS ESC/E(Z) complex
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048863 ISS stem cell differentiation
GO:0061086 ISS negative regulation of histone H3-K27 methylation
GO:0061087 ISS positive regulation of histone H3-K27 methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005590 mtf2 protein_coding Danio_rerio
ENSMUSG00000029267 Mtf2 protein_coding Mus_musculus

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