ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin specific peptidase 21
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143258 USP21 9606 + 1:161159450-161165723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289865 USP21-001 161159479-161165723 protein_coding
  ENST00000368001 USP21-002 161159537-161165723 protein_coding
  ENST00000368002 USP21-201 161159464-161165714 protein_coding
  ENST00000479344 USP21-005 161159521-161160992 protein_coding
  ENST00000482385 USP21-008 161162624-161164822 retained_intron
  ENST00000485277 USP21-009 161163879-161165505 retained_intron
  ENST00000486299 USP21-006 161160744-161162680 processed_transcript
  ENST00000487163 USP21-003 161161363-161165723 retained_intron
  ENST00000492950 USP21-004 161159450-161162368 protein_coding
  ENST00000493054 USP21-007 161163555-161165627 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000289865ENST00000368001ENST00000368002ENST00000485277ENST00000487163ENST00000492950ENST00000493054
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000289865 N/A 1.750±0.80 N/A 2.650±0.00 4.924±3.07
ENST00000368001 1.978±0.19 2.035±0.47 N/A N/A 1.886±1.16
ENST00000368002 N/A 1.863±1.03 N/A N/A 2.165±1.31
ENST00000485277 3.005±0.00 2.577±0.56 7.959±0.00 N/A 4.181±0.90
ENST00000487163 N/A 0.188±0.00 N/A N/A 1.699±0.92
ENST00000492950 N/A 0.572±0.20 N/A N/A 4.459±2.35
ENST00000493054 7.699±0.58 3.063±0.40 16.123±0.00 N/A 6.654±0.42

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003713 ISS transcription coactivator activity
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005575 ND cellular_component
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008234 ISS cysteine-type peptidase activity
GO:0016578 ISS histone deubiquitination
GO:0019784 IDA NEDD8-specific protease activity
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094280 usp21 protein_coding Danio_rerio
ENSMUSG00000053483 Usp21 protein_coding Mus_musculus

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