ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143398 PIP5K1A 9606 + 1:151197949-151249536 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349792 PIP5K1A-001 151198551-151249536 protein_coding
  ENST00000368888 PIP5K1A-003 151198575-151247888 protein_coding
  ENST00000368890 PIP5K1A-002 151198553-151249531 protein_coding
  ENST00000409426 PIP5K1A-015 151198552-151249504 protein_coding
  ENST00000418435 PIP5K1A-004 151213517-151231801 protein_coding
  ENST00000424999 PIP5K1A-014 151198554-151216000 protein_coding
  ENST00000441902 PIP5K1A-016 151198553-151248149 protein_coding
  ENST00000447555 PIP5K1A-011 151197949-151231761 protein_coding
  ENST00000454769 PIP5K1A-017 151198725-151227361 nonsense_mediated_decay
  ENST00000460157 PIP5K1A-013 151236634-151238605 retained_intron
  ENST00000461816 PIP5K1A-009 151224139-151232307 retained_intron
  ENST00000464105 PIP5K1A-007 151233622-151236747 processed_transcript
  ENST00000468772 PIP5K1A-005 151223880-151232345 retained_intron
  ENST00000481713 PIP5K1A-006 151227267-151232641 retained_intron
  ENST00000486048 PIP5K1A-012 151232252-151234367 processed_transcript
  ENST00000486866 PIP5K1A-008 151236634-151240291 retained_intron
  ENST00000489625 PIP5K1A-010 151242112-151248483 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000349792ENST00000368890ENST00000409426ENST00000424999ENST00000481713ENST00000489625
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000349792 9.094±2.49 N/A 16.849±0.00 11.208±5.69
ENST00000368890 2.498±0.00 N/A N/A N/A
ENST00000409426 6.925±2.67 2.178±0.00 6.129±0.00 6.793±3.06
ENST00000424999 N/A N/A N/A 56.955±3.52
ENST00000481713 N/A N/A N/A 46.147±3.72
ENST00000489625 10.464±0.00 N/A N/A 14.688±2.59

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000LW CIL_0000LW_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005847 IDA mRNA cleavage and polyadenylation specificity factor complex
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006644 TAS phospholipid metabolic process
GO:0006650 TAS glycerophospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0006909 TAS phagocytosis
GO:0007165 TAS signal transduction
GO:0008654 IDA phospholipid biosynthetic process
GO:0010761 IEA fibroblast migration
GO:0016307 IEA phosphatidylinositol phosphate kinase activity
GO:0016308 IDA 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016477 NAS cell migration
GO:0016607 IDA nuclear speck
GO:0019900 IDA kinase binding
GO:0030027 IDA lamellipodium
GO:0030216 TAS keratinocyte differentiation
GO:0031532 IMP actin cytoskeleton reorganization
GO:0032587 IDA ruffle membrane
GO:0032863 IMP activation of Rac GTPase activity
GO:0044281 TAS small molecule metabolic process
GO:0046488 IEA phosphatidylinositol metabolic process
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0048041 IMP focal adhesion assembly
GO:0060326 IMP cell chemotaxis
GO:0072661 IMP protein targeting to plasma membrane
GO:0097178 IMP ruffle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024642 pip5k1ab protein_coding Danio_rerio
ENSMUSG00000028126 Pip5k1a protein_coding Mus_musculus

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