ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein disulfide isomerase family A, member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143870 PDIA6 9606 - 2:10783391-10837977 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272227 PDIA6-001 10783391-10812844 protein_coding
  ENST00000381611 PDIA6-201 10783393-10832485 protein_coding
  ENST00000404371 PDIA6-002 10783393-10832485 protein_coding
  ENST00000404824 PDIA6-003 10783861-10837977 protein_coding
  ENST00000458536 PDIA6-005 10819274-10832340 protein_coding
  ENST00000489662 PDIA6-006 10797099-10812754 processed_transcript
  ENST00000540494 PDIA6-202 10783393-10812839 protein_coding
  ENST00000617249 PDIA6-203 10783393-10820864 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000272227ENST00000617249
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000272227 199.652±132.93 175.714±41.95 63.379±0.00 208.874±0.00 189.124±154.00
ENST00000617249 138.558±85.87 N/A N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003756 IBA protein disulfide isomerase activity
GO:0005515 IPI protein binding
GO:0005783 IBA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005793 IDA endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 IEA plasma membrane
GO:0006457 IBA protein folding
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0016853 IEA isomerase activity
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0034976 IBA response to endoplasmic reticulum stress
GO:0043277 IBA apoptotic cell clearance
GO:0044267 TAS cellular protein metabolic process
GO:0045454 IEA cell redox homeostasis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009001 pdia6 protein_coding Danio_rerio
ENSMUSG00000020571 Pdia6 protein_coding Mus_musculus

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