ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: polymerase (RNA) II (DNA directed) polypeptide D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144231 POLR2D 9606 - 2:127846266-127858157 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272645 POLR2D-001 127846266-127858157 protein_coding
  ENST00000409698 POLR2D-003 127847841-127857949 protein_coding
  ENST00000409955 POLR2D-002 127846699-127858117 protein_coding
  ENST00000487079 POLR2D-004 127847241-127858119 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000272645ENST00000409955ENST00000487079
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000272645 6.177±0.80 15.195±3.77 1.240±0.00 5.024±0.00 6.604±4.08
ENST00000409955 3.091±0.00 6.243±1.27 N/A 4.479±0.00 5.551±4.48
ENST00000487079 N/A 7.052±0.97 N/A 6.018±0.00 4.772±1.16

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000288 IBA nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0000932 IBA cytoplasmic mRNA processing body
GO:0003697 IBA single-stranded DNA binding
GO:0003727 IBA single-stranded RNA binding
GO:0003824 IEA catalytic activity
GO:0003899 IEA:IMP DNA-directed RNA polymerase activity
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005665 IDA DNA-directed RNA polymerase II, core complex
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006351 IEA transcription, DNA-templated
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0006367 IBA transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0031369 IBA translation initiation factor binding
GO:0031990 IBA mRNA export from nucleus in response to heat stress
GO:0034402 IBA recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
GO:0044237 IEA cellular metabolic process
GO:0045948 IBA positive regulation of translational initiation
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076509 polr2d protein_coding Danio_rerio
ENSMUSG00000024258 Polr2d protein_coding Mus_musculus

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