ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: kelch-like family member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145332 KLHL8 9606 - 4:87160103-87240314 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273963 KLHL8-001 87160103-87220608 protein_coding
  ENST00000425278 KLHL8-003 87161043-87220525 protein_coding
  ENST00000498875 KLHL8-002 87160249-87220536 protein_coding
  ENST00000504029 KLHL8-006 87170199-87220545 processed_transcript
  ENST00000505388 KLHL8-007 87163883-87220497 processed_transcript
  ENST00000506274 KLHL8-008 87219524-87240314 processed_transcript
  ENST00000506985 KLHL8-004 87162444-87220463 nonsense_mediated_decay
  ENST00000512111 KLHL8-005 87162522-87220268 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000273963ENST00000425278ENST00000498875ENST00000505388ENST00000512111
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000273963 1.453±0.70 0.515±0.00 1.067±0.64
ENST00000425278 0.869±0.24 N/A 0.784±0.45
ENST00000498875 0.748±0.26 1.230±0.00 0.758±0.32
ENST00000505388 N/A N/A 1.239±0.00
ENST00000512111 1.188±0.37 1.252±0.00 0.756±0.61

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000BR CIL_0000BR_0001 CGP
CIL_0000BS CIL_0000BS_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0016567 IDA protein ubiquitination
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0042787 IDA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029312 Klhl8 protein_coding Mus_musculus

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