ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: TBC1 domain containing kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145348 TBCK 9606 - 4:106041599-106321495 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273980 TBCK-001 106041599-106321495 protein_coding
  ENST00000361687 TBCK-002 106046080-106316230 protein_coding
  ENST00000394706 TBCK-003 106046091-106316206 protein_coding
  ENST00000394708 TBCK-006 106046570-106316266 protein_coding
  ENST00000432496 TBCK-201 106046076-106316704 protein_coding
  ENST00000467183 TBCK-004 106046095-106316209 nonsense_mediated_decay
  ENST00000503516 TBCK-013 106232998-106238740 protein_coding
  ENST00000503832 TBCK-011 106247823-106252007 nonsense_mediated_decay
  ENST00000505574 TBCK-010 106244685-106250470 nonsense_mediated_decay
  ENST00000506280 TBCK-005 106251867-106297739 processed_transcript
  ENST00000506384 TBCK-018 106163279-106171240 processed_transcript
  ENST00000506615 TBCK-017 106182353-106230446 processed_transcript
  ENST00000507696 TBCK-009 106295156-106316235 protein_coding
  ENST00000508666 TBCK-012 106232944-106247285 nonsense_mediated_decay
  ENST00000509532 TBCK-019 106251984-106316266 protein_coding
  ENST00000509862 TBCK-008 106262164-106310588 protein_coding
  ENST00000510927 TBCK-007 106046079-106247722 retained_intron
  ENST00000511011 TBCK-016 106171241-106213598 processed_transcript
  ENST00000514689 TBCK-015 106116203-106213718 processed_transcript
  ENST00000515705 TBCK-014 106116319-106213771 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000273980ENST00000394708ENST00000432496ENST00000510927
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000273980 N/A N/A N/A N/A 0.579±0.21
ENST00000394708 N/A 5.284±0.00 N/A N/A 4.598±1.37
ENST00000432496 N/A 3.630±0.63 N/A 8.420±0.00 4.603±1.77
ENST00000510927 3.235±0.00 N/A 3.828±0.00 N/A 6.361±3.39

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002MH CIL_0002MH_0002 CGP
CIL_0006P9 CIL_0006P9_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA:NAS protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005097 IEA Rab GTPase activator activity
GO:0005524 IEA:NAS ATP binding
GO:0006468 IEA:NAS protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032313 IEA regulation of Rab GTPase activity
GO:0032851 IEA positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013667 tbck protein_coding Danio_rerio
ENSMUSG00000028030 Tbck protein_coding Mus_musculus

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