ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: gamma-aminobutyric acid (GABA) A receptor, beta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145864 GABRB2 9606 - 5:161288429-161549044 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274547 GABRB2-201 161288429-161548124 protein_coding
  ENST00000353437 GABRB2-001 161293864-161548227 protein_coding
  ENST00000393959 GABRB2-002 161288429-161546643 protein_coding
  ENST00000517547 GABRB2-006 161293898-161546697 protein_coding
  ENST00000517901 GABRB2-003 161293864-161548135 protein_coding
  ENST00000520240 GABRB2-004 161293864-161548124 protein_coding
  ENST00000522758 GABRB2-005 161459135-161546725 retained_intron
  ENST00000523730 GABRB2-007 161546746-161549044 processed_transcript
  ENST00000612710 GABRB2-202 161329434-161546679 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000353437ENST00000393959ENST00000517547ENST00000517901ENST00000522758ENST00000612710
Transcript ID HAoEC HUVEC
ENST00000353437 0.088±0.00 N/A
ENST00000393959 0.084±0.05 0.004±0.00
ENST00000517547 0.179±0.00 0.042±0.00
ENST00000517901 0.114±0.07 N/A
ENST00000522758 N/A 0.032±0.00
ENST00000612710 0.027±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004890 ISS GABA-A receptor activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005237 IEA inhibitory extracellular ligand-gated ion channel activity
GO:0005254 ISS chloride channel activity
GO:0005515 IEA protein binding
GO:0005829 IEA cytosol
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0007165 IEA signal transduction
GO:0007214 TAS gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007605 IEA sensory perception of sound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0043523 IEA regulation of neuron apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0048666 IEA neuron development
GO:0051932 ISS synaptic transmission, GABAergic
GO:0055085 TAS transmembrane transport
GO:0060119 IEA inner ear receptor cell development
GO:0060384 IEA innervation
GO:0070062 IDA extracellular vesicular exosome
GO:0071420 ISS cellular response to histamine
GO:0090102 IEA cochlea development
GO:1901215 IEA negative regulation of neuron death
GO:1902476 ISS chloride transmembrane transport
GO:1902711 ISS GABA-A receptor complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079586 gabrb2 protein_coding Danio_rerio
ENSMUSG00000007653 Gabrb2 protein_coding Mus_musculus

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