ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: telomeric repeat binding factor (NIMA-interacting) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147601 TERF1 9606 + 8:73008864-73048122 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276602 TERF1-002 73008864-73048122 protein_coding
  ENST00000276603 TERF1-001 73008864-73046471 protein_coding
  ENST00000517390 TERF1-006 73012857-73027036 protein_coding
  ENST00000518695 TERF1-004 73008908-73012505 retained_intron
  ENST00000518874 TERF1-005 73008877-73022280 protein_coding
  ENST00000518961 TERF1-003 73029953-73046975 retained_intron
  ENST00000520783 TERF1-008 73031613-73038804 processed_transcript
  ENST00000522018 TERF1-007 73022233-73038798 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000276602ENST00000276603ENST00000518695ENST00000518961
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000276602 1.839±0.00 1.828±0.85 N/A 3.257±1.60
ENST00000276603 1.563±0.00 2.257±0.71 6.635±0.00 3.918±2.62
ENST00000518695 N/A N/A N/A 0.301±0.05
ENST00000518961 N/A 0.822±0.02 1.293±0.00 0.533±0.23

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003GB CIL_0003GB_0001 CGP
CIL_000132 CIL_000132_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IEP G2/M transition of mitotic cell cycle
GO:0000723 TAS:IEA telomere maintenance
GO:0000781 IDA:IEA chromosome, telomeric region
GO:0000783 IDA nuclear telomere cap complex
GO:0000784 IEA nuclear chromosome, telomeric region
GO:0001309 IDA age-dependent telomere shortening
GO:0003677 NAS:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003691 IDA double-stranded telomeric DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0005819 IDA spindle
GO:0005856 IEA cytoskeleton
GO:0007004 NAS telomere maintenance via telomerase
GO:0007067 IEA mitotic nuclear division
GO:0007094 IMP mitotic spindle assembly checkpoint
GO:0008017 IDA microtubule binding
GO:0008156 IDA negative regulation of DNA replication
GO:0008301 IDA DNA binding, bending
GO:0010834 IMP telomere maintenance via telomere shortening
GO:0031116 IDA positive regulation of microtubule polymerization
GO:0032211 IGI negative regulation of telomere maintenance via telomerase
GO:0032214 NAS negative regulation of telomere maintenance via semi-conservative replication
GO:0042162 IDA:IEA telomeric DNA binding
GO:0042493 IEA response to drug
GO:0042803 IPI:IEA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0045840 IMP positive regulation of mitosis
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0046982 IDA protein heterodimerization activity
GO:0051260 IDA protein homooligomerization
GO:0051974 IGI negative regulation of telomerase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058710 terf1 protein_coding Danio_rerio
ENSMUSG00000025925 Terf1 protein_coding Mus_musculus

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