ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: HECT and RLD domain containing E3 ubiquitin protein ligase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148634 HERC4 9606 - 10:67921899-68075348 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000277817 HERC4-002 67921899-68039967 protein_coding
  ENST00000373700 HERC4-001 67922489-68075348 protein_coding
  ENST00000395185 HERC4-011 68067085-68075301 processed_transcript
  ENST00000395198 HERC4-009 67921908-68075283 protein_coding
  ENST00000412272 HERC4-008 67921908-68075283 protein_coding
  ENST00000427635 HERC4-010 67922484-68073097 nonsense_mediated_decay
  ENST00000460168 HERC4-004 67964792-67990241 retained_intron
  ENST00000463478 HERC4-007 68032819-68038365 retained_intron
  ENST00000473533 HERC4-016 67922484-68075283 nonsense_mediated_decay
  ENST00000480158 HERC4-003 67954200-67956861 processed_transcript
  ENST00000492996 HERC4-006 68067689-68075283 protein_coding
  ENST00000505760 HERC4-012 68067182-68074857 processed_transcript
  ENST00000506515 HERC4-013 68073021-68074137 protein_coding
  ENST00000513996 HERC4-015 68034000-68075257 protein_coding
  ENST00000515753 HERC4-014 68073135-68074193 processed_transcript

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000277817ENST00000373700ENST00000395185ENST00000395198ENST00000412272ENST00000427635ENST00000473533ENST00000480158ENST00000492996
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000277817 N/A 3.184±0.00 N/A N/A N/A
ENST00000373700 N/A 7.091±3.54 N/A 20.475±0.00 8.160±6.87
ENST00000395185 N/A N/A N/A N/A 9.644±4.85
ENST00000395198 1.284±0.00 1.587±0.40 N/A 6.084±0.00 5.724±3.47
ENST00000412272 0.951±0.03 N/A N/A N/A 1.245±0.43
ENST00000427635 N/A 1.387±0.00 N/A N/A N/A
ENST00000473533 2.087±0.00 1.320±0.00 3.975±0.00 N/A N/A
ENST00000480158 N/A N/A N/A N/A 3.606±0.00
ENST00000492996 2.034±0.14 3.091±0.00 N/A N/A 1.341±0.32

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IBA:IEA ubiquitin-protein transferase activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0007283 ISS spermatogenesis
GO:0016874 IEA ligase activity
GO:0030154 IEA cell differentiation
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059936 HERC4 protein_coding Danio_rerio
ENSMUSG00000020064 Herc4 protein_coding Mus_musculus

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