ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: fatty acid desaturase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149485 FADS1 9606 - 11:61799625-61829318 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000350997 FADS1-001 61799625-61817162 protein_coding
  ENST00000421879 FADS1-005 61810826-61829318 protein_coding
  ENST00000424501 FADS1-008 61810742-61816771 nonsense_mediated_decay
  ENST00000433932 FADS1-002 61802058-61816148 protein_coding
  ENST00000448607 FADS1-006 61812589-61829309 protein_coding
  ENST00000460649 FADS1-004 61802218-61804680 protein_coding
  ENST00000466716 FADS1-009 61811005-61816461 protein_coding
  ENST00000473263 FADS1-010 61813257-61816148 protein_coding
  ENST00000491310 FADS1-007 61810973-61816778 protein_coding
  ENST00000496123 FADS1-021 61802836-61812483 processed_transcript
  ENST00000536991 FADS1-022 61802007-61806528 protein_coding
  ENST00000539419 FADS1-020 61812472-61815111 protein_coding
  ENST00000539999 FADS1-013 61803426-61810885 protein_coding
  ENST00000540767 FADS1-016 61810748-61816460 protein_coding
  ENST00000541683 FADS1-015 61814339-61816602 processed_transcript
  ENST00000542506 FADS1-012 61802313-61815291 protein_coding
  ENST00000544309 FADS1-014 61811010-61817197 protein_coding
  ENST00000544696 FADS1-017 61811000-61816108 protein_coding
  ENST00000545245 FADS1-019 61810751-61815132 protein_coding
  ENST00000545405 FADS1-018 61810784-61815148 protein_coding
  ENST00000545986 FADS1-023 61813503-61814649 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000350997
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000350997 16.154±5.65 35.556±0.00 36.003±20.45

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007WT CIL_0007WT_0001 VISTA
CIL_0002MK CIL_0002MK_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000248 TAS C-5 sterol desaturase activity
GO:0005506 IEA iron ion binding
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006629 IEA lipid metabolic process
GO:0006633 IEA fatty acid biosynthetic process
GO:0006636 IEA unsaturated fatty acid biosynthetic process
GO:0007267 NAS cell-cell signaling
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0008654 TAS phospholipid biosynthetic process
GO:0009267 IDA cellular response to starvation
GO:0009744 IEA response to sucrose
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0016020 NAS membrane
GO:0016021 NAS integral component of membrane
GO:0016491 IDA oxidoreductase activity
GO:0016717 IEA oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0019369 IEA arachidonic acid metabolic process
GO:0020037 IEA heme binding
GO:0032868 IEA response to insulin
GO:0033189 IEA response to vitamin A
GO:0033559 TAS unsaturated fatty acid metabolic process
GO:0035900 IEA response to isolation stress
GO:0036109 TAS alpha-linolenic acid metabolic process
GO:0043231 NAS intracellular membrane-bounded organelle
GO:0043651 TAS linoleic acid metabolic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045595 NAS regulation of cell differentiation
GO:0046456 TAS icosanoid biosynthetic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000010663 Fads1 protein_coding Mus_musculus

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