ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ankyrin 3, node of Ranvier (ankyrin G)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151150 ANK3 9606 - 10:60026298-60733490 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280772 ANK3-001 60026298-60389730 protein_coding
  ENST00000355288 ANK3-002 60029690-60141016 protein_coding
  ENST00000373815 ANK3-008 60106022-60139400 protein_coding
  ENST00000373820 ANK3-009 60028868-60082686 protein_coding
  ENST00000373827 ANK3-004 60028401-60733490 protein_coding
  ENST00000459732 ANK3-021 60061921-60064288 protein_coding
  ENST00000460468 ANK3-007 60138517-60166875 protein_coding
  ENST00000465749 ANK3-020 60086543-60088358 retained_intron
  ENST00000467420 ANK3-003 60088273-60114246 protein_coding
  ENST00000469721 ANK3-024 60055776-60059816 retained_intron
  ENST00000474360 ANK3-006 60138517-60166896 protein_coding
  ENST00000480699 ANK3-016 60029700-60051604 processed_transcript
  ENST00000486349 ANK3-017 60138517-60140515 protein_coding
  ENST00000489505 ANK3-025 60029691-60044803 retained_intron
  ENST00000502769 ANK3-011 60029690-60056038 protein_coding
  ENST00000503366 ANK3-005 60029797-60572663 protein_coding
  ENST00000503925 ANK3-010 60234688-60300482 protein_coding
  ENST00000506635 ANK3-012 60134271-60139756 protein_coding
  ENST00000508449 ANK3-022 60082508-60084715 retained_intron
  ENST00000510382 ANK3-018 60507501-60733324 processed_transcript
  ENST00000511043 ANK3-023 60059700-60080620 protein_coding
  ENST00000513049 ANK3-013 60108901-60140040 protein_coding
  ENST00000514197 ANK3-014 60059392-60064288 protein_coding
  ENST00000610321 ANK3-034 60042691-60109054 protein_coding
  ENST00000610901 ANK3-029 60056000-60070463 protein_coding
  ENST00000612776 ANK3-032 60029701-60059430 protein_coding
  ENST00000613207 ANK3-030 60059940-60070283 protein_coding
  ENST00000616444 ANK3-033 60042672-60106059 protein_coding
  ENST00000617800 ANK3-031 60042672-60055832 protein_coding
  ENST00000618080 ANK3-035 60108830-60139087 protein_coding
  ENST00000618374 ANK3-201 60029700-60140675 protein_coding
  ENST00000621739 ANK3-028 60063109-60072569 nonsense_mediated_decay
  ENST00000622427 ANK3-015 60083939-60572909 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000280772ENST00000373820ENST00000373827ENST00000459732ENST00000502769ENST00000503366ENST00000503925ENST00000513049ENST00000618374ENST00000622427
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000280772 N/A 0.248±0.00 N/A N/A 0.082±0.05
ENST00000373820 N/A N/A N/A N/A 0.244±0.09
ENST00000373827 N/A 1.855±0.71 N/A 0.606±0.00 0.332±0.31
ENST00000459732 0.074±0.00 N/A 0.301±0.00 N/A N/A
ENST00000502769 N/A N/A N/A N/A 0.302±0.00
ENST00000503366 N/A 0.643±0.27 N/A N/A 0.270±0.10
ENST00000503925 N/A N/A N/A N/A 0.125±0.00
ENST00000513049 N/A N/A N/A N/A 0.340±0.00
ENST00000618374 N/A N/A N/A N/A 0.063±0.00
ENST00000622427 0.068±0.00 N/A N/A N/A 0.140±0.09

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002W5 CIL_0002W5_0002 CGP
CIL_0000GY CIL_0000GY_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 IMP mitotic cytokinesis
GO:0005200 IMP structural constituent of cytoskeleton
GO:0005515 IPI:IEA protein binding
GO:0005764 IEA lysosome
GO:0005783 TAS endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0005923 IDA tight junction
GO:0007009 IMP plasma membrane organization
GO:0007016 TAS cytoskeletal anchoring at plasma membrane
GO:0007165 IEA signal transduction
GO:0007409 ISS axonogenesis
GO:0007411 IEA axon guidance
GO:0007528 IEA neuromuscular junction development
GO:0008092 ISS cytoskeletal protein binding
GO:0009925 IDA basal plasma membrane
GO:0009986 ISS cell surface
GO:0010628 ISS positive regulation of gene expression
GO:0010650 IEA positive regulation of cell communication by electrical coupling
GO:0010765 ISS positive regulation of sodium ion transport
GO:0014704 ISS intercalated disc
GO:0014731 ISS spectrin-associated cytoskeleton
GO:0016020 IEA membrane
GO:0016323 IDA basolateral plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0019228 ISS neuronal action potential
GO:0030018 IEA Z disc
GO:0030315 ISS T-tubule
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0030507 ISS spectrin binding
GO:0030674 ISS protein binding, bridging
GO:0031594 IEA neuromuscular junction
GO:0033268 ISS node of Ranvier
GO:0033270 IEA paranode region of axon
GO:0034112 IEA positive regulation of homotypic cell-cell adhesion
GO:0042383 IDA sarcolemma
GO:0043001 IMP Golgi to plasma membrane protein transport
GO:0043005 IEA neuron projection
GO:0043034 TAS costamere
GO:0043194 ISS axon initial segment
GO:0043266 ISS regulation of potassium ion transport
GO:0044325 ISS ion channel binding
GO:0045184 IMP establishment of protein localization
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045296 ISS cadherin binding
GO:0045838 ISS positive regulation of membrane potential
GO:0050808 IEA synapse organization
GO:0071709 IMP membrane assembly
GO:0072659 IMP protein localization to plasma membrane
GO:0072660 IGI maintenance of protein location in plasma membrane
GO:0072661 IMP protein targeting to plasma membrane
GO:0090314 IEA positive regulation of protein targeting to membrane
GO:1900827 ISS positive regulation of membrane depolarization during cardiac muscle cell action potential
GO:2000651 ISS positive regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061736 ank3a protein_coding Danio_rerio
ENSDARG00000077582 ank3b protein_coding Danio_rerio
ENSMUSG00000069601 Ank3 protein_coding Mus_musculus

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