ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: eukaryotic translation initiation factor 4E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151247 EIF4E 9606 - 4:98871684-98930637 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280892 EIF4E-002 98880765-98929092 protein_coding
  ENST00000418385 EIF4E-004 98925972-98929125 processed_transcript
  ENST00000450253 EIF4E-001 98871684-98930637 protein_coding
  ENST00000504432 EIF4E-005 98880845-98929125 protein_coding
  ENST00000504472 EIF4E-006 98895122-98929133 processed_transcript
  ENST00000505194 EIF4E-010 98881010-98890898 processed_transcript
  ENST00000505829 EIF4E-009 98887163-98891571 retained_intron
  ENST00000505992 EIF4E-007 98880898-98929133 protein_coding
  ENST00000507665 EIF4E-003 98886351-98929128 retained_intron
  ENST00000511644 EIF4E-008 98880845-98929101 protein_coding
  ENST00000515638 EIF4E-011 98880772-98929125 nonsense_mediated_decay

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000280892ENST00000450253ENST00000505194ENST00000505992ENST00000511644ENST00000515638
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000280892 N/A 13.701±7.91 N/A 7.088±3.65
ENST00000450253 N/A 1.841±0.76 2.642±0.00 1.856±1.51
ENST00000505194 N/A N/A N/A 6.800±0.00
ENST00000505992 N/A 12.901±0.00 N/A 29.915±28.23
ENST00000511644 7.321±0.00 10.194±1.89 29.475±0.00 38.968±6.48
ENST00000515638 5.913±0.00 15.645±5.32 17.201±0.00 22.583±10.56

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008LO CIL_0008LO_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0000339 TAS RNA cap binding
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0003723 IEA RNA binding
GO:0003743 ISS:IEA translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005845 IDA mRNA cap binding complex
GO:0006406 TAS mRNA export from nucleus
GO:0006412 TAS translation
GO:0006413 TAS:IEA translational initiation
GO:0006417 IDA regulation of translation
GO:0008286 TAS insulin receptor signaling pathway
GO:0010467 TAS gene expression
GO:0010494 IDA cytoplasmic stress granule
GO:0016032 IEA viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016281 IDA eukaryotic translation initiation factor 4F complex
GO:0016442 IDA RISC complex
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030324 IEA lung development
GO:0031370 IEA eukaryotic initiation factor 4G binding
GO:0033391 IEA chromatoid body
GO:0043234 IEA protein complex
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013274 eif4eb protein_coding Danio_rerio
ENSDARG00000077012 eif4ea protein_coding Danio_rerio
ENSMUSG00000028156 Eif4e protein_coding Mus_musculus

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