ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152234 ATP5A1 9606 - 18:46080248-46104334 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282050 ATP5A1-201 46084144-46104233 protein_coding
  ENST00000398752 ATP5A1-001 46080248-46098353 protein_coding
  ENST00000585650 ATP5A1-014 46089959-46099352 nonsense_mediated_decay
  ENST00000586523 ATP5A1-013 46084150-46088696 retained_intron
  ENST00000586592 ATP5A1-008 46084150-46098315 nonsense_mediated_decay
  ENST00000587902 ATP5A1-007 46084427-46086584 retained_intron
  ENST00000588390 ATP5A1-019 46094700-46098295 retained_intron
  ENST00000589252 ATP5A1-018 46087427-46098295 protein_coding
  ENST00000589611 ATP5A1-010 46089429-46092198 retained_intron
  ENST00000589869 ATP5A1-003 46088136-46104334 protein_coding
  ENST00000590156 ATP5A1-002 46084150-46098295 nonsense_mediated_decay
  ENST00000590324 ATP5A1-004 46089632-46104233 protein_coding
  ENST00000590406 ATP5A1-005 46089599-46104227 protein_coding
  ENST00000590448 ATP5A1-022 46089759-46104253 retained_intron
  ENST00000590665 ATP5A1-009 46084150-46098296 protein_coding
  ENST00000591267 ATP5A1-015 46093180-46098296 processed_transcript
  ENST00000591981 ATP5A1-020 46089822-46098296 nonsense_mediated_decay
  ENST00000592364 ATP5A1-021 46086127-46098285 nonsense_mediated_decay
  ENST00000592989 ATP5A1-016 46089822-46104273 protein_coding
  ENST00000593152 ATP5A1-202 46084144-46098353 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000282050ENST00000398752ENST00000586523ENST00000587902ENST00000590406ENST00000590665ENST00000592364
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000282050 44.769±23.31 128.427±9.79 18.704±0.00 121.041±0.00 139.120±96.30
ENST00000398752 N/A N/A N/A N/A 0.554±0.09
ENST00000586523 N/A N/A N/A N/A 0.690±0.00
ENST00000587902 211.467±3.76 N/A 67.268±0.00 N/A N/A
ENST00000590406 N/A 158.018±26.90 N/A N/A 5.965±0.00
ENST00000590665 115.038±15.50 131.794±17.73 41.362±0.00 80.839±0.00 69.522±10.01
ENST00000592364 N/A N/A N/A N/A 153.770±14.34

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001937 IMP negative regulation of endothelial cell proliferation
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005739 NAS mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005753 IDA mitochondrial proton-transporting ATP synthase complex
GO:0005759 TAS mitochondrial matrix
GO:0005886 IDA plasma membrane
GO:0006200 IDA ATP catabolic process
GO:0006629 ISS lipid metabolic process
GO:0006754 IC ATP biosynthetic process
GO:0008180 IDA COP9 signalosome
GO:0009790 ISS embryo development
GO:0015986 IEA ATP synthesis coupled proton transport
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0015992 IEA proton transport
GO:0016020 IDA membrane
GO:0016820 IEA hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0016887 IDA ATPase activity
GO:0022857 IC transmembrane transporter activity
GO:0022904 TAS respiratory electron transport chain
GO:0033178 IEA proton-transporting two-sector ATPase complex, catalytic domain
GO:0042288 IDA MHC class I protein binding
GO:0042776 IC mitochondrial ATP synthesis coupled proton transport
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045261 IEA proton-transporting ATP synthase complex, catalytic core F(1)
GO:0046034 IEA ATP metabolic process
GO:0046933 ISS:IEA proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 IEA proton-transporting ATPase activity, rotational mechanism
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010149 atp5a1 protein_coding Danio_rerio
ENSMUSG00000025428 Atp5a1 protein_coding Mus_musculus

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